N Otake
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Explore the profile of N Otake including associated specialties, affiliations and a list of published articles.
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Articles
123
Citations
372
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Recent Articles
1.
Asano T, Nakamura K, Fujii H, Horichi N, Ohmori T, Hasegawa K, et al.
Br J Cancer
. 2005 Mar;
92(8):1486-92.
PMID: 15798770
KRN 8602 (MX2) is a novel morpholino anthracycline derivative having the chemical structure 3'-deamino-3'-morpholino-13-deoxo-10-hydroxycarminomycin hydrochloride. To investigate the mechanisms of resistance to MX2, we established an MX2-resistant phenotype (K562/MX2) of...
2.
Fujisaki S, Fujisaki T, Yoshida J, Fujisaki Y, Mitani M, Nakamura M, et al.
Jpn J Antibiot
. 2000 Jun;
53(3):135-56.
PMID: 10834146
Chronic hepatitis B and C virus infections have been characterized by the pathophysiological features with a high incidence of progression to cirrhosis and development of hepatocellular carcinoma. The viral persistence...
3.
Suzuki K, Kurokawa K, Suzuki T, Okazaki H, Otake N, Imai K, et al.
Int Urol Nephrol
. 1998 Aug;
30(3):267-71.
PMID: 9696331
To assess the effect of hyperbaric oxygen (HBO) therapy on radiation cystitis, clinical and histopathological characteristics were examined. Three women with radiation cystitis were treated with HBO therapy. Macrohaematuria was...
4.
Hamada S, Kataoka T, Woo J, Yamada A, Yoshida T, Nishimura T, et al.
Biol Pharm Bull
. 1997 Oct;
20(9):1017-9.
PMID: 9331989
Gallic acid (GA) and chebulagic acid (CA) were isolated from the extract of a herbal medicine, kashi (myrobalans: the fruit of Terminalia chebula) as active principles that blocked the cytotoxic...
5.
Yasaka N, Otake N, Furue M, Tamaki K
Dermatology
. 1997 Jan;
194(2):162-5.
PMID: 9094466
We report a 50-year-old Japanese woman with a 3-year history of systemic lupus erythematosus treated with prednisolone, who had diffuse plane yellowish macules mainly on the upper arm. The lesion...
6.
Muroi M, Suehara K, Wakusawa H, Suzuki K, Sato T, Nishimura T, et al.
J Antibiot (Tokyo)
. 1996 Nov;
49(11):1119-26.
PMID: 8982341
The nonapeptide leucinostatin A (LSA) inhibited syncytium formation without profoundly affecting HN glycoprotein synthesis in Newcastle disease virus (NDV)-infected BHK cells. At similar doses of LSA, cytopathic effect and infectious...
7.
Kamishohara M, Kawai H, Sakai T, Uchida T, Tsuruo T, Otake N
Cancer Chemother Pharmacol
. 1996 Jan;
38(6):495-8.
PMID: 8823489
The inhibitory effect of KRN5500, a spicamycin derivative, on the growth of hepatic metastasis of the tissue polypeptide antigen (TPA)-producing human colon cancer COL-1 was examined in severe combined immunodeficient...
8.
Sakai T, Kawai H, Kamishohara M, Odagawa A, Suzuki A, Uchida T, et al.
J Antibiot (Tokyo)
. 1995 Dec;
48(12):1467-80.
PMID: 8557605
New derivatives of spicamycin modified at the fatty acid moieties of the molecule were synthesized and their structure-activity relationships were examined. The antitumor activity was greatly influenced by modification of...
9.
Taniguchi M, Kataoka T, Suzuki H, Uramoto M, Ando M, Arao K, et al.
Biosci Biotechnol Biochem
. 1995 Nov;
59(11):2064-7.
PMID: 8541643
Costunolide and dehydrocostus lactone were isolated from an extract of mokko (Saussurea lappa Clarke) as inhibitors of killing activity of cytotoxic T lymphocytes (CTL). Mokko lactone was also isolated as...
10.
Sakai T, Shindo K, Odagawa A, Suzuki A, Kawai H, Kobayashi K, et al.
J Antibiot (Tokyo)
. 1995 Aug;
48(8):899-900.
PMID: 7592040
No abstract available.