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N M Ratcliffe

Explore the profile of N M Ratcliffe including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 482
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Recent Articles
1.
Aggio R, White P, Jayasena H, de Lacy Costello B, Ratcliffe N, Probert C
Aliment Pharmacol Ther . 2016 Nov; 45(1):82-90. PMID: 27862117
Background: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, there are...
2.
McGuire N, Ewen R, de Lacy Costello B, Garner C, Probert C, Vaughan K, et al.
Meas Sci Technol . 2016 May; 25(6). PMID: 27212803
Rapid volatile profiling of stool sample headspace was achieved using a combination of short multi-capillary chromatography column (SMCC), highly sensitive heated metal oxide semiconductor (MOS) sensor and artificial neural network...
3.
Shepherd S, McGuire N, de Lacy Costello B, Ewen R, Jayasena D, Vaughan K, et al.
J Breath Res . 2014 Mar; 8(2):026001. PMID: 24674940
There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that...
4.
de Lacy Costello B, Amann A, Al-Kateb H, Flynn C, Filipiak W, Khalid T, et al.
J Breath Res . 2014 Jan; 8(1):014001. PMID: 24421258
A compendium of all the volatile organic compounds (VOCs) emanating from the human body (the volatolome) is for the first time reported. 1840 VOCs have been assigned from breath (872),...
5.
de Lacy Costello B, Ledochowski M, Ratcliffe N
J Breath Res . 2013 Mar; 7(2):024001. PMID: 23470880
Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test...
6.
Khalid T, Saad S, Greenman J, de Lacy Costello B, Probert C, Ratcliffe N
J Breath Res . 2013 Mar; 7(1):017114. PMID: 23446221
The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should...
7.
de Lacy Costello B, Ewen R, Ewer A, Garner C, Probert C, Ratcliffe N, et al.
J Breath Res . 2011 Mar; 2(3):037023. PMID: 21386183
A gas chromatography/mass spectrometry (GCMS) analysis of the headspace from the faeces of neonates was undertaken to record the volatiles associated with preterm babies on a neonatal unit. The compounds...
8.
Smith S, Burden H, Persad R, Whittington K, de Lacy Costello B, Ratcliffe N, et al.
J Breath Res . 2011 Mar; 2(3):037022. PMID: 21386182
First-void urine samples were obtained from 24 elderly, asymptomatic men (median age 62.9 years). The headspace above pH adjusted urine samples were extracted using a carboxen/polydimethylsiloxane solid phase micro-extraction fibre...
9.
de Lacy Costello B, Ewen R, Ratcliffe N, Richards M
J Breath Res . 2011 Mar; 2(3):037017. PMID: 21386178
For breath analyses, volatile detectors capable of sensing extremely low concentrations in the sub-ppm range are required. Novel room temperature sensors were fabricated based on ultraviolet light activation of nanoparticulate...
10.
de Lacy Costello B, Ewen R, Ratcliffe N
J Breath Res . 2011 Mar; 2(3):037011. PMID: 21386172
A sensor array system was constructed incorporating electrochemical sensors for hydrogen, carbon monoxide, hydrogen sulfide and ethanol, a ceramic sensor for total volatiles and a dye-based optical ammonia sensor. The...