N M Moutsopoulos
Overview
Explore the profile of N M Moutsopoulos including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
235
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Recent Articles
1.
Silva L, Divaris K, Bugge T, Moutsopoulos N
J Dent Res
. 2023 Jul;
102(9):972-978.
PMID: 37506226
The hemostatic and inflammatory systems work hand in hand to maintain homeostasis at mucosal barrier sites. Among the factors of the hemostatic system, fibrin is well recognized for its role...
2.
Moutsopoulos N, Konkel J
Mucosal Immunol
. 2020 Aug;
13(6):852-854.
PMID: 32843674
No abstract available.
3.
Abusleme L, OGorman H, Dutzan N, Greenwell-Wild T, Moutsopoulos N
J Dent Res
. 2020 Apr;
99(6):721-729.
PMID: 32345105
Commensal microbiomes exert critical functions at barrier sites. In particular, establishment of the commensal microbiome after birth dictates immune functionality and tissue homeostasis at mucosal surfaces. To investigate the establishment...
4.
Moutsopoulos N, Moutsopoulos H
Oral Dis
. 2018 Feb;
24(1-2):22-25.
PMID: 29480644
In the oral cavity, the immune system is constantly exposed to unique tissue-specific signals, including a rich community of commensal microbes and their metabolites, continuous tissue damage from mastication, and...
5.
Konkel J, Moutsopoulos N
J Dent Res
. 2017 Oct;
97(2):128-131.
PMID: 29028424
Our recent work highlights unique requirements for the induction of Th17 cells at the oral/gingival mucosal barrier. Unlike other barrier sites, such as the skin and gastrointestinal tract, we found...
6.
Abusleme L, Moutsopoulos N
Oral Dis
. 2016 Oct;
23(7):854-865.
PMID: 27763707
Interleukin-17 (IL-17) is a multifaceted cytokine with diverse roles in both immune protection and also immunopathology. IL-17 has a well-recognized role in immune surveillance at mucosal and barrier surfaces, but...
7.
Moutsopoulos N, Lionakis M, Hajishengallis G
J Dent Res
. 2015 Apr;
94(6):753-8.
PMID: 25900229
In recent years, the study of genetic defects arising from inborn errors in immunity has resulted in the discovery of new genes involved in the function of the immune system...
8.
Betts K, Abusleme L, Freeman A, Sarmadi M, Fahle G, Pittaluga S, et al.
J Clin Virol
. 2015 Jan;
63:46-50.
PMID: 25600604
We present a 17-year old girl with DOCK-8 deficiency, severe untreated oral HSV-1 infection and associated aggressive periodontitis. DOCK-8 deficiency is a primary immunodeficiency, caused by biallelicloss-of-function mutations in the...
9.
Sales K, Friis S, Abusleme L, Moutsopoulos N, Bugge T
Oncogene
. 2014 Dec;
34(35):4664-72.
PMID: 25486433
Deregulation of matriptase is a consistent feature of human epithelial cancers and correlates with poor disease outcome. We have previously shown that matriptase promotes multi-stage squamous cell carcinogenesis in transgenic...
10.
Moutsopoulos N, Katsifis G, Angelov N, Leakan R, Sankar V, Pillemer S, et al.
Ann Rheum Dis
. 2008 Jan;
67(10):1437-43.
PMID: 18198195
Objective: To provide insight into the clinical failure of the tumour necrosis factor alpha (TNFalpha) inhibitor, etanercept, in primary Sjögren syndrome (pSS), an extensive analysis of the systemic immune profile...