N L First
Overview
Explore the profile of N L First including associated specialties, affiliations and a list of published articles.
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208
Citations
1674
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Recent Articles
1.
Misirlioglu M, Page G, Sagirkaya H, Kaya A, Parrish J, First N, et al.
Proc Natl Acad Sci U S A
. 2006 Dec;
103(50):18905-10.
PMID: 17142320
Global activation of the embryonic genome is the most critical event in early mammalian development. After fertilization, a rich supply of maternal proteins and RNAs support development whereas a number...
2.
Beyhan Z, Forsberg E, Eilertsen K, Kent-First M, First N
Mol Reprod Dev
. 2006 Aug;
74(1):18-27.
PMID: 16941691
Developmental abnormalities associated with the cloning process suggest that reprogramming of donor nuclei into an embryonic state may not be fully completed in most of the cloned animals. One of...
3.
Mitalipova M, Beyhan Z, First N
Cloning
. 2002 Mar;
3(2):59-67.
PMID: 11900640
We report herein the establishment of three bovine pluripotent embryonic cell lines derived from 8-16-cell precompacting embryos. Two cell lines were cultured for 10 passages and underwent spontaneous differentiation. One...
4.
Sakaguchi M, Dominko T, Yamauchi N, Leibfried-Rutledge M, Nagai T, First N
Reproduction
. 2002 Mar;
123(1):135-42.
PMID: 11869195
The mechanism for the accelerating effects of epidermal growth factor (EGF) and insulin-like growth factor I (IGF-I) on the meiotic cell cycle of bovine oocytes cultured in vitro was investigated....
5.
Segev H, Memili E, First N
Zygote
. 2001 May;
9(2):123-33.
PMID: 11358320
Gene expression at the onset of bovine embryogenesis is developmentally regulated and histone deacetylases (HDACs) have been shown to play a key role in the control of gene expression during...
6.
Sakaguchi M, Dominko T, Leibfried-Rutledge M, Nagai T, First N
Theriogenology
. 2001 Feb;
54(8):1327-42.
PMID: 11192191
The effects of a combination of EGF and IGF-I (GFs) on the progress of meiosis and on their developmental competence were examined in cumulus-enclosed bovine oocytes. Exposure to GFs in...
7.
Memili E, First N
Zygote
. 2000 Jun;
8(1):87-96.
PMID: 10840878
Early embryonic development is largely dependent on maternal RNAs and proteins synthesised during oogenesis. Zygotic transcription is an essential event that occurs at a species-specific time after fertilization. In the...
8.
Beyhan Z, Johnson L, First N
Theriogenology
. 2000 Mar;
52(1):35-48.
PMID: 10734404
The objective of this study was to examine preimplantation development and sperm aster characteristics of bovine male and female embryos produced by using spermatozoa sorted for the X or Y...
9.
Memili E, First N
Biol Reprod
. 1999 Oct;
61(5):1198-207.
PMID: 10529265
The objective of this study was to examine the timing and mechanisms involved in transcription initiation in bovine embryos. Transcriptional activity and its regulation were explored by labeling 1-cell zygotes...
10.
Fulka Jr J, First N, Fulka1 J, Moor R
Hum Reprod
. 1999 Jun;
14(6):1582-7.
PMID: 10357980
The high incidence of chromosomally abnormal human embryos is frequently assumed to be due to a lack of checkpoint controls operating during early embryogenesis. In our study we have analysed...