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N Krone

Explore the profile of N Krone including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 20
Citations 353
Followers 0
Related Specialties
Endocrinology
General Medicine
Biochemistry
Top 10 Co-Authors
F G Riepe
H P Schwarz
W G Sippell
A A Roscher
C-J Partsch
A Braun
S A Wudy
W Arlt
F C G J Sweep
D A Rees
Published In
Exp Clin Endocrinol Diabetes
J Clin Endocrinol Metab
Eur J Endocrinol
Clin Endocrinol (Oxf)
Clin Chem
Affiliations
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Recent Articles
1.
GENETICS IN ENDOCRINOLOGY: Approaches to molecular genetic diagnosis in the management of differences/disorders of sex development (DSD): position paper of EU COST Action BM 1303 ‘DSDnet’
Audi L, Ahmed S, Krone N, Cools M, McElreavey K, Holterhus P, et al.
Eur J Endocrinol . 2018 Oct; 179(4):R197-R206. PMID: 30299888
The differential diagnosis of differences or disorders of sex development (DSD) belongs to the most complex fields in medicine. It requires a multidisciplinary team conducting a synoptic and complementary approach...
2.
Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the fdx1 co-factors in zebrafish
Weger M, Diotel N, Weger B, Beil T, Zaucker A, Eachus H, et al.
J Neuroendocrinol . 2018 Feb; 30(4):e12586. PMID: 29486070
The spatial and temporal expression of steroidogenic genes in zebrafish has not been fully characterised. Because zebrafish are increasingly employed in endocrine and stress research, a better characterisation of steroidogenic...
3.
Steroid hormone analysis in diagnosis and treatment of DSD: position paper of EU COST Action BM 1303 'DSDnet'
Kulle A, Krone N, Holterhus P, Schuler G, Greaves R, Juul A, et al.
Eur J Endocrinol . 2017 Feb; 176(5):P1-P9. PMID: 28188242
Disorders or differences in sex development (DSD) comprise a heterogeneous group of conditions with an atypical sex development. For optimal diagnosis, highly specialised laboratory analyses are required across European countries....
4.
Natural history of retinopathy in children and young people with type 1 diabetes
Dhillon N, Karthikeyan A, Castle A, Dodson P, Hogler W, Kirk J, et al.
Eye (Lond) . 2016 Apr; 30(7):987-91. PMID: 27101752
PurposeTo describe the prevalence and natural history of retinopathy in a cohort of children and young people with type 1 diabetes attending a tertiary hospital diabetes clinic.MethodsWe analysed retinopathy screening...
5.
Adrenal Steroid Metabolites Accumulating in Congenital Adrenal Hyperplasia Lead to Transactivation of the Glucocorticoid Receptor
Pijnenburg-Kleizen K, Engels M, Mooij C, Griffin A, Krone N, Span P, et al.
Endocrinology . 2015 Jul; 156(10):3504-10. PMID: 26207344
Patients with congenital adrenal hyperplasia (CAH) are often clinically less severely affected by cortisol deficiency than anticipated from their enzymatic defect. We hypothesize that adrenal steroid hormone precursors that accumulate...
6.
Relationship between final height and health outcomes in adults with congenital adrenal hyperplasia: United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE)
Han T, Conway G, Willis D, Krone N, Rees D, Stimson R, et al.
J Clin Endocrinol Metab . 2014 Jun; 99(8):E1547-55. PMID: 24878054
Context: Treatment of congenital adrenal hyperplasia (CAH) in childhood focuses on growth and development and adult final height (FH) is a measure of effective treatment. We hypothesized that shorter adults...
7.
Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling
Lavery G, Idkowiak J, Sherlock M, Bujalska I, Ride J, Saqib K, et al.
Eur J Endocrinol . 2012 Nov; 168(2):K19-26. PMID: 23132696
Context: Inactivating mutations in the enzyme hexose-6-phosphate dehydrogenase (H6PDH, encoded by H6PD) cause apparent cortisone reductase deficiency (ACRD). H6PDH generates cofactor NADPH for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1, encoded by...
8.
Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia
Han T, Stimson R, Rees D, Krone N, Willis D, Conway G, et al.
Clin Endocrinol (Oxf) . 2012 Sep; 78(2):197-203. PMID: 22998134
Background: Adults with congenital adrenal hyperplasia (CAH) are treated with a wide variety of glucocorticoid treatment regimens. Objective, Design And Methods: To test whether drug dose and timing of glucocorticoid...
9.
No correlation between androgen receptor CAG and GGN repeat length and the degree of genital virilization in females with 21-hydroxylase deficiency
Welzel M, Schwarz H, Hedderich J, Dorr H, Binder G, Bramswig J, et al.
J Clin Endocrinol Metab . 2010 Mar; 95(5):2443-50. PMID: 20233785
Context: In 21-hydroxylase (CYP21A2) deficiency (21OHD), the level of in vitro enzymatic function allows for classification of mutation groups (null, A, B, C) and prediction of disease severity. However, genital...
10.
Extreme hyponatremia in an infant with congenital adrenal hypoplasia due to a novel NR0B1 (DAX-1) mutation
Holzinger A, Riepe F, Krone N, Grasser M, Munch H, Schwarz H
Klin Padiatr . 2008 Aug; 220(5):287-90. PMID: 18716981
Background: Extreme hyponatremia (<105 mmol/l) has rarely been reported in infants. It is potentially life-threatening and requires intensive care treatment. Patient: We report on a male infant with absence of...