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N Kloting

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Articles 23
Citations 481
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Recent Articles
1.
Kosacka J, Nowicki M, Paeschke S, Baum P, Bluher M, Kloting N
Diabetol Metab Syndr . 2018 Mar; 10:13. PMID: 29507613
Background: Wistar Ottawa Karlsburg W (RT1u) rats (WOKW) are a model of the metabolic syndrome (MetS). Adipose tissue (AT) and peripheral nerves of WOKW rats exhibit up-regulated autophagy and inflammation...
2.
Hesselbarth N, Kunath A, Kern M, Gericke M, Mejhert N, Ryden M, et al.
Int J Obes (Lond) . 2017 Jul; 41(12):1815-1823. PMID: 28736440
Background/objectives: Replication initiator 1 (Repin1) gene encodes for a zinc-finger protein and has been implicated in the regulation of adipocyte cell size and glucose transport in vitro. Here, we investigate...
3.
Kralisch S, Hoffmann A, Kloting N, Bachmann A, Kratzsch J, Bluher M, et al.
Diabetes Metab . 2017 Feb; 43(5):465-468. PMID: 28214129
No abstract available.
4.
Wagner I, Kloting N, Atanassova N, Savchuk I, Sprote C, Kiess W, et al.
Mol Cell Endocrinol . 2016 Aug; 437:154-162. PMID: 27544779
Obesity is a global health problem and impacts negatively on levels of testosterone and quality of sperm production. At present little is known about mechanisms that attenuate testicular function in...
5.
Weingarten A, Turchetti L, Krohn K, Kloting I, Kern M, Kovacs P, et al.
Int J Obes (Lond) . 2016 Jul; 40(12):1832-1840. PMID: 27460604
Background: The genetic architecture of obesity is multifactorial. We have previously identified a quantitative trait locus (QTL) on rat chromosome 10 in a F2 cross of Wistar Ottawa Karlsburg (WOKW)...
6.
Wagner I, Flehmig G, Scheuermann K, Loffler D, Korner A, Kiess W, et al.
Horm Metab Res . 2016 Jun; 48(9):589-94. PMID: 27355242
Insulin-like peptide 5 (INSL5) is a gut hormone produced by L-cells in the colorectal epithelium and may play a role in the regulation of metabolic processes. The biological role of...
7.
Kilian T, Kloting N, Bluher M, Beck-Sickinger A
Int J Obes (Lond) . 2015 Oct; 40(4):698-705. PMID: 26499442
Introduction/objectives: The protein delta homolog 1 (DLK1) has been reported to have an important role as inhibitor of adipogenesis. Understanding its mode of action can be a promising approach to...
8.
Kosacka J, Kern M, Kloting N, Paeschke S, Rudich A, Haim Y, et al.
Mol Cell Endocrinol . 2015 Mar; 409:21-32. PMID: 25818883
Background: Pathophysiology of obesity is closely associated with enhanced autophagy in adipose tissue (AT). Autophagic process can promote survival or activate cell death. Therefore, we examine the occurrence of autophagy...
9.
Ebert T, Hopf L, Wurst U, Bachmann A, Kralisch S, Lossner U, et al.
Nutr Metab Cardiovasc Dis . 2014 May; 24(9):1027-34. PMID: 24813306
Background And Aims: The adipokine adipocyte fatty acid binding protein (AFABP) is positively associated with the development of the metabolic syndrome, diabetes mellitus, and cardiovascular disease. We hypothesized that AFABP...
10.
Kosacka J, Nowicki M, Bluher M, Baum P, Stockinger M, Toyka K, et al.
Exp Neurol . 2013 Oct; 250:125-35. PMID: 24095727
Objective: Wistar Ottawa Karlsburg W (RT1(u)) rats (WOKW) develop obesity, dyslipidemia, moderate hypertension, hyperinsulinemia and impaired glucose tolerance prone to induce peripheral neuropathy (PN). Autophagy has been shown to prevent...