N K Gibbs
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Explore the profile of N K Gibbs including associated specialties, affiliations and a list of published articles.
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41
Citations
157
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Recent Articles
1.
Gibbs N, Angus C, Dixon S, Parry C, Meier P
Appl Health Econ Health Policy
. 2023 Mar;
21(3):395-403.
PMID: 36894828
Background: Health economic models aim to provide decision makers with information that is contextually relevant, understandable and credible. This requires ongoing engagement throughout the research project between the modeller and...
2.
Traynor N, Johnson B, Gibbs N
Toxicol In Vitro
. 2010 Jul;
10(5):619-24.
PMID: 20650243
The phototoxic potential of several non-steroidal anti-inflammatory drugs and quinolone antibiotics was assessed using the photohaemolysis assay. In this system, human erythrocytes are irradiated (UVA radiation 320-400 nm) from below...
3.
McLoone P, Man I, Yule S, Fluitman A, van Loveren H, Norval M, et al.
Photodermatol Photoimmunol Photomed
. 2004 Mar;
20(2):76-80.
PMID: 15030591
Background/purpose: Ultraviolet (UV) exposure of mammalian skin induces local and systemic immunosuppression. In mice it has been proposed that systemic immunosuppression is mediated by an UV-induced cytokine cascade involving systemic...
4.
Termorshuizen F, Garssen J, Norval M, Koulu L, Laihia J, Leino L, et al.
Int Immunopharmacol
. 2002 Jan;
2(2-3):263-75.
PMID: 11811930
Recent studies on the immunosuppressive effects of ultraviolet radiation (UVR) and the related resistance to infections in rodents and humans are presented. The waveband dependency of trans-to-cis isomerisation of urocanic...
5.
Kidd S, Meunier J, Traynor N, Marrot L, Gibbs N
J Photochem Photobiol B
. 2001 Feb;
58(1):26-31.
PMID: 11195849
The fluoroquinolone antibiotic, lomefloxacin, is phototoxic in human skin exposed to UVA radiation, photosensitises DNA strand breaks and pyrimidine dimers in human keratinocytes in vitro, and is phototumorigenic in mouse...
6.
Spielmann H, MULLER L, Averbeck D, Balls M, Brendler-Schwaab S, Castell J, et al.
Altern Lab Anim
. 2000 Dec;
28(6):777-814.
PMID: 11105201
No abstract available.
7.
Man I, Wainwright N, Gibbs N, Ferguson J
Photodermatol Photoimmunol Photomed
. 2000 Nov;
16(5):211-5.
PMID: 11068860
One aspect of bath photochemotherapy (PUVA) that requires clarification is the duration of psoralen-induced cutaneous photosensitisation under conditions simulating clinical use. Using a half back comparison study technique, we investigated...
8.
Synergistic activation of p53-dependent transcription by two cooperating damage recognition pathways
Blaydes J, Craig A, Wallace M, Ball H, Traynor N, Gibbs N, et al.
Oncogene
. 2000 Aug;
19(34):3829-39.
PMID: 10951576
High level activation of p53-dependent transcription occurs following cellular exposure to genotoxic damaging agents such as UV-C, while ionizing radiation damage does not induce a similarly potent induction of p53-dependent...
9.
Al-Ajmi H, Dawe R, Renwick A, Macklin B, Ferguson J, Gibbs N
Photodermatol Photoimmunol Photomed
. 2000 Jul;
16(3):111-5.
PMID: 10885439
The calcium antagonist nifedipine absorbs ultraviolet A (UVA) radiation and readily photodegrades in vitro to a toxic nitroso-pyridine photoproduct. We examined whether whole body exposure of normal subjects to sunbed...
10.
Traynor N, Barratt M, Lovell W, Ferguson J, Gibbs N
Toxicol In Vitro
. 2000 May;
14(3):275-83.
PMID: 10806378
Many therapeutic drugs induce phototoxic skin responses following exposure to solar or artificial ultraviolet radiation sources. Several in vitro model systems have been developed to predict drug phototoxicity but none...