N J Philp
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Explore the profile of N J Philp including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
403
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Recent Articles
1.
Philp N, Yoon H, Lombardi L
Am J Physiol Cell Physiol
. 2001 Apr;
280(5):C1319-26.
PMID: 11287345
Monocarboxylate transporters (MCTs) are a family of highly homologous membrane proteins that mediate the 1:1 transport of a proton and a lactate ion. In chicken, MCT3 is preferentially expressed in...
2.
Grollman E, Philp N, McPhie P, Ward R, Sauer B
Biochemistry
. 2000 Aug;
39(31):9351-7.
PMID: 10924129
Monocarboxylate transporters (MCTs) comprise a group of highly homologous proteins that reside in the plasma membrane of almost all cells and which mediate the 1:1 electroneutral transport of a proton...
3.
Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2
Yoon H, Donoso L, Philp N
Genomics
. 1999 Sep;
60(3):366-70.
PMID: 10493836
Lactate transport across cell membranes is mediated by a family of proton-coupled monocarboxylate transporters (MCTs). The retinal pigment epithelium (RPE) expresses a unique member of this family, MCT3. A portion...
4.
Yoon H, Philp N
Exp Eye Res
. 1998 Nov;
67(4):417-24.
PMID: 9820789
MCT3 is a monocarboxylate transporter that is specifically expressed on the basolateral membrane of retinal pigment epithelial cells (RPE). In these studies the temporal expression of MCT3 during ocular development...
5.
Philp N, Yoon H, Grollman E
Am J Physiol
. 1998 Jun;
274(6):R1824-8.
PMID: 9841555
The retinal pigment epithelium (RPE) forms the outer blood-retinal barrier and regulates the movement of nutrients, water, and ions between the choroidal blood supply and the retina. The transport properties...
6.
Yoon H, Fanelli A, Grollman E, Philp N
Biochem Biophys Res Commun
. 1997 May;
234(1):90-4.
PMID: 9168967
The retinal pigment epithelium transports lactate between two tissue compartments, the interphotoreceptor matrix and the choriocapillaris. In this report we describe a 2.45-kb cDNA isolated from a chick cDNA RPE...
7.
Matesic D, Philp N, Murray J, Liebman P
J Cell Sci
. 1992 Sep;
103 ( Pt 1):157-66.
PMID: 1429903
Bovine rod outer segment (ROS) preparations contain a major 58 kDa protein doublet that was identified by immunoblot as tubulin. Quantification by gel densitometry showed that the total amount of...
8.
Philp N, Yoon M, Hock R
Exp Eye Res
. 1990 Aug;
51(2):191-8.
PMID: 2117547
Retinal pigmented epithelial cells are adherent at their basal surface to Bruch's membrane and at their apical surface to the neural retina. We examined the expression and distribution of two...
9.
Philp N, Nachmias V, Lee D, Stramm L, Buzdygon B
Exp Eye Res
. 1988 Jan;
46(1):21-8.
PMID: 2830126
It has been suggested that rhodopsin may have a direct role in the attachment of shed rod outer segments (ROS) to retinal pigmented epithelial (RPE) cells initiating the events which...
10.
Philp N, Chang W, Long K
FEBS Lett
. 1987 Dec;
225(1-2):127-32.
PMID: 2826235
We examined the intracellular distribution of three proteins involved in the cyclic GMP cascade of visual transduction; cGMP phosphodiesterase, the alpha-subunit of G-protein and arrestin. In adult rats, light-induced changes...