N J Dimmock
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Explore the profile of N J Dimmock including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
1738
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Recent Articles
1.
Marriott A, Dimmock N
Rev Med Virol
. 2009 Dec;
20(1):51-62.
PMID: 20041441
Defective interfering (DI) virus is simply defined as a spontaneously generated virus mutant from which a critical portion of the virus genome has been deleted. At least one essential gene...
2.
Reading S, Dimmock N
Arch Virol
. 2007 May;
152(6):1047-59.
PMID: 17516034
Neutralization is the ability of antibody to bind to and inactivate virus infectivity under defined conditions in vitro. Most neutralizing antibodies also protect animals in vivo, but protection is more...
3.
Mann A, Marriott A, Balasingam S, Lambkin R, Oxford J, Dimmock N
Vaccine
. 2006 Apr;
24(20):4290-6.
PMID: 16621180
Defective interfering (DI) virus RNAs result from major deletions in full-length viral RNAs that occur spontaneously during de novo RNA synthesis. These RNAs are packaged into virions that are by...
4.
Duhaut S, Dimmock N
J Virol Methods
. 2003 Feb;
108(1):75-82.
PMID: 12565156
Naturally produced defective influenza virus has antiviral activity and, in sufficient amount, can protect mice from lethal influenza, irrespective of the virus subtype causing the disease. However, such defective virus...
5.
Duhaut S, Dimmock N
J Gen Virol
. 2002 Jan;
83(Pt 2):403-411.
PMID: 11807233
The presence of at least 80-90 and more typically around 200 nucleotides (nt) at the 5' end of the virion-sense RNA in all naturally occurring defective influenza A virus RNAs...
6.
McInerney T, Dimmock N
AIDS Res Hum Retroviruses
. 2002 Jan;
17(17):1645-54.
PMID: 11779352
De novo infecting HIV-1 or virus released from an infected cell in vivo attaches relatively quickly to a target cell, but the rate of fusion-entry of such virus is slow,...
7.
Edwards M, Dimmock N
J Virol
. 2001 Oct;
75(21):10208-18.
PMID: 11581389
In standard neutralization (STAN), virus and antibody are reacted together before inoculation of target cells, and inhibition of almost any of the processes concerned in the early interaction of virus...
8.
Reading S, Edwards M, Dimmock N
J Virol Methods
. 2001 Sep;
98(2):167-9.
PMID: 11576644
Improving the virus particle:infectious unit ratio is a continuing goal for animal virologists. It is demonstrated for an influenza A virus that decreasing the size of the inoculum volume to...
9.
Wilson J, Nokes D, Dimmock N
J Med Virol
. 2001 Jul;
64(4):560-8.
PMID: 11468744
The prevention of viral infection by vaccination relies on stimulating an appropriate immune response in order to reduce the probability with which a virus can establish an infection. Post-vaccination antibody...
10.
Edwards M, Dimmock N
J Gen Virol
. 2001 May;
82(Pt 6):1387-1395.
PMID: 11369883
H9-D3-4R2 (referred to as H9), a murine monoclonal HA1-specific IgG3, recognizes an epitope within antigenic site Cb of influenza virus A/PR/8/34 (H1N1). At 50% neutralization, inhibition of virus-mediated fusion was...