N Ginovart
Overview
Explore the profile of N Ginovart including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
857
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Recent Articles
1.
Wilson A, Ginovart N, Schmidt M, Meyer J, Threlkeld P, Houle S
J Med Chem
. 2016 Aug;
44(2):280.
PMID: 27518803
No abstract available.
2.
Guttman M, Boileau I, Warsh J, Saint-Cyr J, Ginovart N, McCluskey T, et al.
Eur J Neurol
. 2007 Apr;
14(5):523-8.
PMID: 17437611
Early post-mortem data suggest that damage to brain serotonin neurones might play a role in some features (e.g., depression) of Parkinson's disease (PD). However, it is not known whether such...
3.
Sun W, Ginovart N, Ko F, Seeman P, Kapur S
Mol Pharmacol
. 2003 Jan;
63(2):456-62.
PMID: 12527818
Competition with endogenous dopamine (DA) is usually invoked to explain changes in [(11)C]raclopride binding observed after amphetamine administration in animals and humans. This account has recently been questioned because a...
4.
Ginovart N, Wilson A, Meyer J, Hussey D, Houle S
J Cereb Blood Flow Metab
. 2001 Nov;
21(11):1342-53.
PMID: 11702049
[(11) C]-DASB, namely [(11) C]-3-amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile, is a new highly selective radioligand for the in vivo visualization of the serotonin transporter (SERT) using positron emission tomography (PET). The current study evaluates...
5.
Meyer J, Wilson A, Ginovart N, Goulding V, Hussey D, Hood K, et al.
Am J Psychiatry
. 2001 Nov;
158(11):1843-9.
PMID: 11691690
Objective: Selective serotonin reuptake inhibitors are commonly used to treat major depression; however, the percentage of serotonin (5-HT) transporter (5-HTT) sites occupied during clinical dosing is unknown. This study measured...
6.
Houle S, Ginovart N, Hussey D, Meyer J, Wilson A
Eur J Nucl Med
. 2000 Dec;
27(11):1719-22.
PMID: 11105830
Two novel radioligands, N,N-dimethyl-2-(2-amino-4-methoxyphenylthio) b enzylamine (DAPP) and (N,N-dimethyl-2-(2-amino-4-cyanophenylthio) benzylamine (D ASB), were radiolabeled with carbon-11 and evaluated as in vivo probes of the serotonin transporter (SERT) using positron emission...
7.
Broussolle E, Lucking C, Ginovart N, Pollak P, Remy P, Durr A
Neurology
. 2000 Sep;
55(6):877-9.
PMID: 10994015
+Parkin gene mutations cause a form of early-onset autosomal recessive PD with neuronal loss in the substantia nigra and no Lewy bodies. The authors present a PET [18F]-dopa study of...
8.
Wilson A, Ginovart N, Schmidt M, Meyer J, Threlkeld P, Houle S
J Med Chem
. 2000 Aug;
43(16):3103-10.
PMID: 10956218
A series of four 2-(phenylthio)araalkylamines have been radiolabeled with (11)C and evaluated as potential radiotracers for imaging the serotonin transporter (SERT) by positron emission tomography (PET). All four candidates display...
9.
Backman L, Ginovart N, Dixon R, Wahlin T, Wahlin A, Halldin C, et al.
Am J Psychiatry
. 2000 Mar;
157(4):635-7.
PMID: 10739428
Objective: The study examined the influence of losses in dopaminergic function on age-related cognitive deficits. Method: Eleven healthy subjects (21-68 years of age) completed a set of cognitive tasks used...
10.
Farde L, Andree B, Ginovart N, Halldin C, Thorberg S
Neuropsychopharmacology
. 2000 Mar;
22(4):422-9.
PMID: 10700661
The serotonin 5-hydroxytryptamine-1A (5-HT(1A)) receptor subtype is of central interest in research, particularly in the area of pathophysiology and pharmacological treatment of psychiatric disorders. Robalzotan (generic name for NAD-299) is...