N Divecha
Overview
Explore the profile of N Divecha including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1067
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Recent Articles
1.
Fiume R, Faenza I, Sheth B, Poli A, Vidalle M, Mazzetti C, et al.
Int J Mol Sci
. 2019 Jun;
20(12).
PMID: 31248120
Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast array of signalling pathways to control cell proliferation, migration, survival and differentiation. PPIns are differentially present in...
2.
Muris D, Verschoor T, Divecha N, Michalides R
Eur J Cancer
. 2002 Aug;
38(13):1775-82.
PMID: 12175695
The Rho-like guanine triphosphate (GTP)ases become activated by extracellular ligands and regulate a wide variety of biological processes, including cell motility, spreading of cells, cytoskeletal organisation and transcriptional activity. We...
3.
Meijer H, Berrie C, Iurisci C, Divecha N, Musgrave A, Munnik T
Biochem J
. 2001 Nov;
360(Pt 2):491-8.
PMID: 11716778
Polyphosphoinositides play an important role in membrane trafficking and cell signalling. In plants, two PtdInsP isomers have been described, PtdIns3P and PtdIns4P. Here we report the identification of a third,...
4.
Clarke J, Letcher A, Dsantos C, Halstead J, Irvine R, Divecha N
Biochem J
. 2001 Jul;
357(Pt 3):905-10.
PMID: 11463365
Previous data suggest the existence of discrete pools of inositol lipids, which are components of a nuclear phosphoinositide (PI) cycle. However, it is not known whether the contents of these...
5.
Halstead J, Roefs M, Ellson C, DAndrea S, Chen C, Dsantos C, et al.
Curr Biol
. 2001 Apr;
11(6):386-95.
PMID: 11301249
Background: Phosphatidylinositol-3,4,5-trisphosphate [PtdIns(3,4,5)P(3)] is a key second messenger found ubiquitously in higher eukaryotic cells. The activation of Class I phosphoinositide 3-kinases and the subsequent production of PtdIns(3,4,5)P(3) is an important...
6.
Divecha N, Roefs M, Halstead J, DAndrea S, Oomen L, Saqib K, et al.
EMBO J
. 2000 Oct;
19(20):5440-9.
PMID: 11032811
Phosphoinositides are localized in various intracellular compartments and can regulate a number of intracellular functions, such as cytoskeletal dynamics and membrane trafficking. Phospholipase Ds (PLDs) are regulated enzymes that hydrolyse...
7.
Hinchliffe K, Ciruela A, Morris J, Divecha N, Irvine R
Biochem Soc Trans
. 2000 Aug;
27(4):657-61.
PMID: 10917661
No abstract available.
8.
DSantos C, Clarke J, Roefs M, Halstead J, Divecha N
Eur J Histochem
. 2000 Jun;
44(1):51-60.
PMID: 10868293
No abstract available.
9.
Divecha N, Clarke J, Roefs M, Halstead J, DSantos C
Cell Mol Life Sci
. 2000 May;
57(3):379-93.
PMID: 10823239
It is now clear that phosphoinositides, which play a major role in the regulation of a variety of cellular processes in the cytoplasm, are found within the nucleus. Their role...
10.
Ciruela A, Hinchliffe K, Divecha N, Irvine R
Biochem J
. 2000 Mar;
346 Pt 3:587-91.
PMID: 10698683
Type II phosphatidylinositol phosphate kinases (PIPkins) have recently been found to be primarily phosphatidylinositol 5-phosphate 4-kinases, and their physiological role remains unclear. We have previously shown that a Type II...