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N Dear

Explore the profile of N Dear including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 127
Followers 0
Related Specialties
Biochemistry
Genetics
Science
Top 10 Co-Authors
T Boehm
T H Rabbitts
K Matena
W Morose
L C Wu
C H Mak
M Richard
S Wells
S Polley
M Charles
Published In
Nucleic Acids Res
Genomics
Proc Natl Acad Sci U S A
Lab Anim
Public Health Action
Affiliations
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Recent Articles
1.
Identification of TB space-time clusters and hotspots in Ouest , Haiti, 2011-2016
Dismer A, Charles M, Dear N, Louis-Jean J, Barthelemy N, Richard M, et al.
Public Health Action . 2021 Jun; 11(2):101-107. PMID: 34159071
Background: Haiti has the highest incidence rate of TB in the Western Hemisphere, with an estimated 170 cases per 100,000 in 2019. Since 2010, control efforts have focused on targeted...
2.
Analysis of breeding and pathology helps refine management practices of a large-scale N'-ethyl-N'-nitrosourea mouse mutagenesis programme
Smith A, Polley S, Wells S, Stewart M, Vizor L, Humphreys J, et al.
Lab Anim . 2008 Nov; 43(1):1-10. PMID: 18987059
N'-ethyl-N'-nitrosourea (ENU) is a powerful germline mutagen used in conjunction with phenotype-driven screens to generate novel mouse mutants. ENU also induces genetic lesions in somatic cells and dosage requires optimization...
3.
Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily
Matena K, Boehm T, Dear N
Genomics . 1998 Mar; 48(1):117-20. PMID: 9503024
CAPN5 and CAPN6 are recently identified human and mouse genes lacking a calmodulin-like domain with homology to the calpain family of proteases. To clarify their relationship to the known calpains,...
4.
A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution
Dear N, Matena K, Vingron M, Boehm T
Genomics . 1997 Oct; 45(1):175-84. PMID: 9339374
Calpains are calcium-dependent intracellular nonlysosomal proteases that are believed to participate in signal transduction. In vertebrates, five different calpains have so far been identified, of which three, mu-, m-, and...
5.
Expression of peptides encoded by exons in cloned mammalian DNA
Kreissig S, Schuddekopf K, Dear N, Boehm T
Nucleic Acids Res . 1996 Nov; 24(21):4358-9. PMID: 8932395
New synthetic approaches, such as combinatorial chemistry, provide a rich source of potential drug candidates. At the same time, the human genome initiative and other large-scale sequencing projects provide a...
6.
Molecular cloning of a zinc finger protein which binds to the heptamer of the signal sequence for V(D)J recombination
Wu L, Mak C, Dear N, Boehm T, Foroni L, Rabbitts T
Nucleic Acids Res . 1993 Nov; 21(22):5067-73. PMID: 8255760
The somatic V(D)J recombination for the assembly of the Ig and TCR genes is mediated by the recombination signal sequences (Rss) and the V(D)J recombinase. A cDNA clone was isolated...
7.
HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24
Kennedy M, Gonzalez-Sarmiento R, Kees U, Lampert F, Dear N, Boehm T, et al.
Proc Natl Acad Sci U S A . 1991 Oct; 88(20):8900-4. PMID: 1681546
A common chromosomal abnormality in childhood T-cell acute leukemia is a translocation, t(10;14) (q24;q11), that together with the variant t(7;10)(q35;q24) is present in up to 7% of this tumor type....