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N D Meeker

Explore the profile of N D Meeker including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 192
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Recent Articles
1.
Blackburn J, Liu S, Raiser D, Martinez S, Feng H, Meeker N, et al.
Leukemia . 2012 Apr; 26(9):2069-78. PMID: 22538478
NOTCH1 pathway activation contributes to the pathogenesis of over 60% of T-cell acute lymphoblastic leukemia (T-ALL). While Notch is thought to exert the majority of its effects through transcriptional activation...
2.
Rudner L, Brown K, Dobrinski K, Bradley D, Garcia M, Smith A, et al.
Oncogene . 2011 May; 30(41):4289-96. PMID: 21552289
T-cell acute lymphoblastic leukemia (T-ALL) is a challenging clinical entity with high rates of induction failure and relapse. To discover the genetic changes occurring in T-ALL, and those contributing to...
3.
Frazer J, Meeker N, Rudner L, Bradley D, Smith A, Demarest B, et al.
Leukemia . 2009 Jun; 23(10):1825-35. PMID: 19516274
T-cell neoplasias are common in pediatric oncology, and include acute lymphoblastic leukemia (T-ALL) and lymphoblastic lymphoma (T-LBL). These cancers have worse prognoses than their B-cell counterparts, and their treatments carry...
4.
Blankenhorn E, Butterfield R, Rigby R, Cort L, Giambrone D, McDermott P, et al.
J Immunol . 2000 Mar; 164(6):3420-5. PMID: 10706738
Pertussis toxin (PTX) is a potent ancillary adjuvant used to elicit several different autoimmune diseases, including experimental allergic encephalomyelitis (EAE). To delineate the genetics of PTX effect in EAE, we...
5.
Meeker N, Stafford A, Lunceford J, Avner P, Ma R, Teuscher C
Mamm Genome . 1999 Aug; 10(9):858-63. PMID: 10441735
An important approach to understanding complex diseases is to reduce them into well-characterized subphenotypes that are under monogenic control. One such example is Bordetella pertussis toxin-induced histamine sensitization in mice,...
6.
Meeker N, Hickey W, Korngold R, Hansen W, Sudweeks J, Wardell B, et al.
Proc Natl Acad Sci U S A . 1995 Jun; 92(12):5684-8. PMID: 7777570
The existence of immunoregulatory genes conferring dominant resistance to autoimmunity is well documented. In an effort to better understand the nature and mechanisms of action of these genes, we utilized...
7.
Wardell B, Michael S, Tung K, Todd J, Blankenhorn E, McEntee K, et al.
Proc Natl Acad Sci U S A . 1995 May; 92(11):4758-62. PMID: 7761397
Mice thymectomized at three days of age (D3Tx) develop during adulthood a variety of organ-specific autoimmune diseases, including autoimmune ovarian dysgenesis (AOD). The phenotypic spectrum of AOD is characterized by...
8.
Robison R, Tung K, Meeker N, Monson F, Teuscher C
J Reprod Immunol . 1994 May; 26(3):251-60. PMID: 7990076
Experimental allergic orchitis is an organ-specific autoimmune disease characterized by inflammatory infiltrates associated with the seminiferous tubules of the testes. Orchitis is often, but not always, accompanied by aspermatogenesis in...
9.
Teuscher C, Meeker N, Livingstone K, Sudweeks J, Griffith J, Wardell B, et al.
J Reprod Immunol . 1994 May; 26(3):233-49. PMID: 7990075
Experimental allergic orchitis (EAO) can be induced actively and passively in mice by either immunization with mouse testicular homogenate (MTH) in conjunction with the appropriate adjuvants or by transferring CD4+...
10.
Sudweeks J, Todd J, Blankenhorn E, Wardell B, Woodward S, Meeker N, et al.
Proc Natl Acad Sci U S A . 1993 Apr; 90(8):3700-4. PMID: 8475118
Pertussis toxin (PTX) is the primary component responsible for eliciting the majority of biological activities associated with Bordetella pertussis, including the induction of several tissue-adjuvant models of organ-specific autoimmune disease....