N Crawford
Overview
Explore the profile of N Crawford including associated specialties, affiliations and a list of published articles.
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Articles
146
Citations
916
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0
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Recent Articles
1.
Marshall H, Koehler A, Wang B, AHoure M, Gold M, Quinn H, et al.
Vaccine
. 2020 Jul;
38(37):5914-5922.
PMID: 32712083
Background: Four-component meningococcal B (4CMenB) vaccine is licensed in many countries but has had limited use in adolescents despite this age group being at increased risk of meningococcal disease. Objectives:...
2.
Johnston M, Nicoll J, Redmond K, Smyth P, Greene M, McDaid W, et al.
J Control Release
. 2020 Jun;
324:610-619.
PMID: 32504778
Pancreatic cancer is usually advanced and drug resistant at diagnosis. A potential therapeutic approach outlined here uses nanoparticle (NP)-based drug carriers, which have unique properties that enhance intra-tumor drug exposure...
3.
Mitchell D, Crawford N, Newham B, Newton J
Aust N Z J Psychiatry
. 2020 Jan;
54(6):609-619.
PMID: 31973563
Objective: To determine the efficacy, safety and acceptability as well as the patient demographics of three newly developed emergency department-embedded Psychiatric Assessment and Planning Units located in Metropolitan Melbourne at...
4.
Castle A, Crawford N
Thromb Haemost
. 2019 Feb;
42(1):1630-1633.
PMID: 30781923
Blood platelets contain microtubule proteins (tubulin and HMWs) which can be polymerised "in vitro" to form structures which resemble the microtubules seen in the intact platelet. Platelet tubulin is composed...
5.
Majkut J, Sgobba M, Holohan C, Crawford N, Logan A, Kerr E, et al.
Nat Commun
. 2014 Mar;
5:3350.
PMID: 24577104
Death receptor activation triggers recruitment of FADD, which via its death effector domain (DED) engages the DEDs of procaspase 8 and its inhibitor FLIP to form death-inducing signalling complexes (DISCs)....
6.
Riley J, Hutchinson R, McArt D, Crawford N, Holohan C, Paul I, et al.
Cell Death Dis
. 2013 Dec;
4:e951.
PMID: 24309938
Non-small cell lung carcinoma remains by far the leading cause of cancer-related deaths worldwide. Overexpression of FLIP, which blocks the extrinsic apoptotic pathway by inhibiting caspase-8 activation, has been identified...
7.
Crawford N, Stasik I, Holohan C, Majkut J, McGrath M, Johnston P, et al.
Cell Death Dis
. 2013 Jul;
4:e733.
PMID: 23868066
Malignant pleural mesothelioma (MPM) is a highly pro-inflammatory malignancy that is rapidly fatal and increasing in incidence. Cytokine signaling within the pro-inflammatory tumor microenvironment makes a critical contribution to the...
8.
Paul I, Chacko A, Stasik I, Busacca S, Crawford N, McCoy F, et al.
Cell Death Dis
. 2012 Dec;
3:e449.
PMID: 23254292
Failure to efficiently induce apoptosis contributes to cisplatin resistance in non-small-cell lung cancer (NSCLC). Although BCL-2-associated X protein (BAX) and BCL-2 antagonist killer (BAK) are critical regulators of the mitochondrial...
9.
Jurney C, Haddad J, Crawford N, Miller A, Van Winkle T, Vite C, et al.
J Vet Intern Med
. 2009 Jul;
23(4):871-4.
PMID: 19566852
Background: Polymicrogyria is a disorder of cerebrocortical migration resulting in increased numbers of small, disorganized gyri. This disorder occurs in Standard Poodles and in cattle. Objectives: To describe the clinical,...
10.
Wilson T, Redmond K, McLaughlin K, Crawford N, Gately K, OByrne K, et al.
Cell Death Differ
. 2009 Jun;
16(10):1352-61.
PMID: 19543235
We found that procaspase 8 was overexpressed in non-small-cell lung cancers (NSCLCs) compared with matched normal tissues. The caspase 8 inhibitor FLICE-inhibitory protein (FLIP) was also overexpressed in the majority...