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N C Hughes-Jones

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Articles 113
Citations 950
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Hughes-Jones N
Vox Sang . 2000 Aug; 78 Suppl 2:75-7. PMID: 10938933
No abstract available.
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Hughes-Jones N, Bye J, Gorick B, Marks J, Ouwehand W
Br J Haematol . 1999 Jun; 105(3):811-6. PMID: 10354152
Antibodies to the D antigen of the Rh system use a restricted set of immunoglobulin V and J gene segments, especially VH DP50 and DP63, JH6, Vlambda DPL16 and Jlambda...
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ROUILLAC C, Colin Y, Hughes-Jones N, Beolet M, DAmbrosio A, Cartron J, et al.
Blood . 1995 May; 85(10):2937-44. PMID: 7742554
The RH blood group locus from RhD-positive donors is composed of two closely related genes, RHCE and RHD, encoding the Cc/Ee and D antigens, respectively. The major Rh antigen, D,...
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Hughes-Jones N
Lancet . 1995 Feb; 345(8948):502-3. PMID: 7861880
No abstract available.
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Garner S, Gorick B, Lai W, Brown D, Taverner J, Hughes-Jones N, et al.
Vox Sang . 1995 Jan; 68(3):169-76. PMID: 7625074
Sera containing anti-D, taken from 44 RhD-negative women with RhD-positive infants, were tested in antibody-dependent cellular cytotoxicity (ADCC) and monocyte monolayer assays (MMA) which used similar target and effector cell...
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Hughes-Jones N, Gorick B, Bye J, Finnern R, Scott M, Voak D, et al.
Br J Haematol . 1994 Sep; 88(1):180-6. PMID: 7803241
We previously reported the initial characterization of five human single-chain Fv (scFv) antibody fragments specific for the blood group antigens B, D(Rh), E(Rh), Kpb and HI. The scFvs were isolated...
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Marks J, Ouwehand W, Bye J, Finnern R, Gorick B, Voak D, et al.
Biotechnology (N Y) . 1993 Oct; 11(10):1145-9. PMID: 7764095
We have isolated human antibody fragments with binding specificities against the blood group antigens of the ABO and I blood group systems (B and HI), of the Rh system (D...
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Griffiths A, Malmqvist M, Marks J, Bye J, Embleton M, McCafferty J, et al.
EMBO J . 1993 Feb; 12(2):725-34. PMID: 7679990
Recently we demonstrated that human antibody fragments with binding activities against foreign antigens can be isolated from repertoires of rearranged V-genes derived from the mRNA of peripheral blood lymphocytes (PBLs)...