N C De Lanerolle
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Explore the profile of N C De Lanerolle including associated specialties, affiliations and a list of published articles.
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41
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1118
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Recent Articles
1.
Bandak F, Ling G, Bandak A, De Lanerolle N
Handb Clin Neurol
. 2015 Feb;
127:89-104.
PMID: 25702211
Explosive blast shock waves and blunt impact to the head are two types of loading shown to result in mild traumatic brain injury (mTBI). While mTBI from these two causes...
2.
Gomes W, Lado F, De Lanerolle N, Takahashi K, Pan C, Hetherington H
Magn Reson Med
. 2007 Jul;
58(2):230-5.
PMID: 17654595
Reduced hippocampal N-acetyl aspartate (NAA) is commonly observed in patients with advanced, chronic temporal lobe epilepsy (TLE). It is unclear, however, whether an NAA deficit is also present during the...
3.
Bjornsen L, Eid T, Holmseth S, Danbolt N, Spencer D, De Lanerolle N
Neurobiol Dis
. 2006 Nov;
25(2):319-30.
PMID: 17112731
Temporal lobe epilepsy (TLE) with hippocampal sclerosis is associated with high extracellular glutamate levels, which could trigger seizures. Down-regulation of glial glutamate transporters GLAST (EAAT1) and GLT-1 (EAAT2) in sclerotic...
4.
Eid T, Thomas M, Spencer D, Runden-Pran E, Lai J, Malthankar G, et al.
Lancet
. 2004 Jan;
363(9402):28-37.
PMID: 14723991
Background: High extracellular glutamate concentrations have been identified as a likely trigger of epileptic seizures in mesial temporal lobe epilepsy (MTLE), but the underlying mechanism remains unclear. We investigated whether...
5.
Zaveri H, Duckrow R, De Lanerolle N, Spencer S
Epilepsia
. 2001 Jun;
42(6):725-30.
PMID: 11422326
Purpose: Two subtypes of temporal lobe epilepsy (TLE) can be defined through clinical observations and analysis of hippocampal tissue resected during surgical procedures for intractable TLE: (a) mesial temporal sclerosis...
6.
Brines M, Ghezzi P, Keenan S, Agnello D, De Lanerolle N, Cerami C, et al.
Proc Natl Acad Sci U S A
. 2000 Sep;
97(19):10526-31.
PMID: 10984541
Erythropoietin (EPO), recognized for its central role in erythropoiesis, also mediates neuroprotection when the recombinant form (r-Hu-EPO) is directly injected into ischemic rodent brain. We observed abundant expression of the...
7.
Jiang W, Duong T, De Lanerolle N
Epilepsia
. 1999 Jan;
40(1):5-19.
PMID: 9924896
Purpose: Single and repeated hyperthermic seizures were induced in rats beginning at age 22 days to determine the neuroanatomic consequences to the hippocampus and to compare these changes with those...
8.
Xie H, Brines M, De Lanerolle N
Epilepsy Res
. 1998 Oct;
32(1-2):140-53.
PMID: 9761316
Mobile genetic elements termed transposons have been increasingly implicated in human disease. The small transposon mariner is widespread within non-vertebrate genomes and causes mutation by replication, excision, and insertion of...
9.
De Lanerolle N, Eid T, von Campe G, Kovacs I, Spencer D, Brines M
Eur J Neurosci
. 1998 Sep;
10(5):1687-703.
PMID: 9751141
The AMPA-type glutamate receptor subunits GluR1 and GluR2/3 were localized by immunohistochemistry with subunit-specific antibodies in hippocampi removed surgically from patients with temporal lobe epilepsy for the control of seizures....
10.
OConnor E, Sontheimer H, Spencer D, De Lanerolle N
Epilepsia
. 1998 May;
39(4):347-54.
PMID: 9578024
Purpose: We studied Na+ channel expression and the ability to generate action potential (AP)-like responses in primary cultures of human astrocytes by whole cell patch-clamp recording techniques. Methods: Tissue samples...