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Myriam Fernandez-Sendin

Explore the profile of Myriam Fernandez-Sendin including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 159
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Recent Articles
1.
Arrizabalaga L, Di Trani C, Fernandez-Sendin M, Bella A, Russo-Cabrera J, Gomar C, et al.
J Nanobiotechnology . 2025 Feb; 23(1):113. PMID: 39962479
Peritoneal carcinomatosis is an advanced stage of cancer with very limited treatment options. Locoregional immunotherapy is being evaluated as a way to improve efficacy and limit toxicity. This study assessed...
2.
Gomar C, Di Trani C, Bella A, Arrizabalaga L, Gonzalez-Gomariz J, Fernandez-Sendin M, et al.
J Immunother Cancer . 2024 Apr; 12(4). PMID: 38631714
Background: Lymphocytic choriomeningitis virus (LCMV) belongs to the Arenavirus family known for inducing strong cytotoxic T-cell responses in both mice and humans. LCMV has been engineered for the development of...
3.
Bella A, Arrizabalaga L, Di Trani C, Gonzalez-Gomariz J, Gomar C, Russo-Cabrera J, et al.
J Immunother Cancer . 2023 Nov; 11(11). PMID: 37918917
Background: Peritoneal carcinomatosis is an advanced stage of cancer in which the disease has spread to the peritoneal cavity. In order to restore antitumor immunity subverted by tumor cells in...
4.
Di Trani C, Cirella A, Arrizabalaga L, Alvarez M, Bella A, Fernandez-Sendin M, et al.
Mol Ther Nucleic Acids . 2023 Aug; 33:599-616. PMID: 37637207
IL-12 is a potent cytokine for cancer immunotherapy. However, its systemic delivery as a recombinant protein has shown unacceptable toxicity in the clinic. Currently, the intratumoral injection of IL-12-encoding mRNA...
5.
Di Trani C, Cirella A, Arrizabalaga L, Bella A, Fernandez-Sendin M, Russo-Cabrera J, et al.
Oncoimmunology . 2022 Dec; 12(1):2147317. PMID: 36531687
Previous studies have shown that local delivery of tumor antigen-specific CD8 T lymphocytes engineered to transiently express single-chain IL-12 mRNA is highly efficacious. Peritoneal dissemination of cancer is a frequent...
6.
Cirella A, Bolanos E, Di Trani C, de Andrea C, Sanchez-Gregorio S, Etxeberria I, et al.
Cancer Immunol Res . 2022 Dec; 11(2):184-198. PMID: 36478221
IL12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs, and viral vectors. To improve antitumor effects, we have experimentally tested the combination of...
7.
Bella A, Arrizabalaga L, Di Trani C, Fernandez-Sendin M, Teijeira A, Russo-Cabrera J, et al.
Int Rev Cell Mol Biol . 2022 Aug; 371:117-131. PMID: 35964998
Ovarian cancer often spreads out of the ovary before a patient is diagnosed and is the deadliest gynecological malignancy. The aggressiveness of ovarian cancer is determined by the progression in...
8.
Bella A, Arrizabalaga L, Di Trani C, Cirella A, Fernandez-Sendin M, Gomar C, et al.
Oncoimmunology . 2022 Jul; 11(1):2098657. PMID: 35859732
Recombinant-modified vaccinia virus Ankara (rMVA) is known to elicit potent antitumor immune responses in preclinical models due to its inherent ability to activate the innate immune system and the activation...
9.
Dunai C, Ames E, Ochoa M, Fernandez-Sendin M, Melero I, Simonetta F, et al.
Int Rev Cell Mol Biol . 2022 Jul; 370:65-122. PMID: 35798507
Natural killer (NK) cells are innate lymphocytes that control tumor progression by not only directly killing cancer cells, but also by regulating other immune cells, helping to orchestrate a coordinated...
10.
Di Trani C, Cirella A, Arrizabalaga L, Fernandez-Sendin M, Bella A, Aranda F, et al.
Int Rev Cell Mol Biol . 2022 Jul; 369:107-141. PMID: 35777862
Cytokines are pleiotropic soluble proteins used by immune cells to orchestrate a coordinated response against pathogens and malignancies. In cancer immunotherapy, cytokine-based drugs can be developed potentiating pro-inflammatory cytokines or...