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Muralimohan T Reddy

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Articles 5
Citations 222
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Recent Articles
1.
Amantana A, Moulton H, Cate M, Reddy M, Whitehead T, Hassinger J, et al.
Bioconjug Chem . 2007 Jun; 18(4):1325-31. PMID: 17583927
Objective: Conjugation of arginine-rich cell-penetrating peptide (CPP) to phosphorodiamidate morpholino oligomers (PMO) has been shown to enhance cytosolic and nuclear delivery of PMO. However, the in vivo disposition of CPP-PMO...
2.
Ko Y, Devi G, London C, Kayas A, Reddy M, Iversen P, et al.
J Urol . 2004 Aug; 172(3):1140-4. PMID: 15311058
Purpose: Androgen receptor (AR) has a pivotal role in the growth and proliferation of prostate cancer (PCa). Even in advanced stages of PCa AR continues to be expressed and appears...
3.
Moulton H, Nelson M, Hatlevig S, Reddy M, Iversen P
Bioconjug Chem . 2004 Mar; 15(2):290-9. PMID: 15025524
Although the sequence specificity, biostability, and low toxicity of PMO (phosphorodiamidate morpholino oligomers) make them good antisense agents to study gene function, their limited ability to cross cell membranes limits...
4.
Knapp D, Mata J, Reddy M, Devi G, Iversen P
Anticancer Drugs . 2003 Jan; 14(1):39-47. PMID: 12544257
Chemotherapy resistance is a significant obstacle in lung cancer therapy, and has been found to frequently correlate with amplification and overexpression of the c-myc oncogene. Earlier studies have shown that...
5.
Arora V, Knapp D, Reddy M, Weller D, Iversen P
J Pharm Sci . 2002 Apr; 91(4):1009-18. PMID: 11948540
Antisense phosphorodiamidate Morpholino oligomers (PMO) are resistant to degradation by cellular hydrolases, DNases, RNases, and phosphodiesterases, but remain sensitive to prolonged exposure to low pH. The present studies evaluate the...