Muna Aryal
Overview
Explore the profile of Muna Aryal including associated specialties, affiliations and a list of published articles.
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15
Citations
748
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0
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Recent Articles
1.
Zhao W, Li Q, He P, Li C, Aryal M, Fabiilli M, et al.
J Control Release
. 2024 Sep;
375:552-573.
PMID: 39276800
Organic nanocrystals, particularly those composed of conjugated molecules, hold immense potential for various applications. However, their practical utility is often hindered by the challenge of achieving stable aqueous dispersions, which...
2.
Aryal M, Azadian M, Hart A, Macedo N, Zhou Q, Rosenthal E, et al.
J Control Release
. 2022 Jul;
349:434-442.
PMID: 35798095
Intrathecal drug delivery is routinely used in the treatment and prophylaxis of varied central nervous system conditions, as doing so allows drugs to directly bypass the blood-brain barrier. However, the...
3.
Aryal M, Porter T
Neuromolecular Med
. 2021 Aug;
24(1):23-34.
PMID: 34406634
Nearly thirty thousand incidences of primary and 300 thousand incidences of metastatic brain cancer are diagnosed in the USA each year. It has a high mortality rate and is often...
4.
Kim C, Guo Y, Velalopoulou A, Leisen J, Motamarry A, Ramajayam K, et al.
Theranostics
. 2021 Jun;
11(15):7276-7293.
PMID: 34158850
Effective drug delivery in brain tumors remains a major challenge in oncology. Although local hyperthermia and stimuli-responsive delivery systems, such as thermosensitive liposomes, represent promising strategies to locally enhance drug...
5.
Zhou Q, Vega Leonel J, Santoso M, Wilson C, van den Berg N, Chan C, et al.
Sci Rep
. 2021 Mar;
11(1):5710.
PMID: 33707521
The prognosis for high-grade glioma (HGG) remains dismal and the extent of resection correlates with overall survival and progression free disease. Epidermal growth factor receptor (EGFR) is a biomarker heterogeneously...
6.
Wang J, Di Ianni T, Vyas D, Huang Z, Park S, Hosseini-Nassab N, et al.
Front Neurosci
. 2020 Aug;
14:675.
PMID: 32760238
A long-standing goal of translational neuroscience is the ability to noninvasively deliver therapeutic agents to specific brain regions with high spatiotemporal resolution. Focused ultrasound (FUS) is an emerging technology that...
7.
Aryal M, Papademetriou I, Zhang Y, Power C, McDannold N, Porter T
Ultrasound Med Biol
. 2019 Apr;
45(7):1733-1742.
PMID: 31010598
Magnetic resonance image-guided focused ultrasound has emerged as a viable non-invasive technique for the treatment of central nervous system-related diseases/disorders. Application of mechanical and thermal effects associated with focused transcranial...
8.
Wang J, Aryal M, Zhong Q, Vyas D, Airan R
Neuron
. 2018 Nov;
100(3):728-738.e7.
PMID: 30408444
Being able to noninvasively modulate brain activity, where and when an experimenter desires, with an immediate path toward human translation is a long-standing goal for neuroscience. To enable robust perturbation...
9.
Sun T, Zhang Y, Power C, Alexander P, Sutton J, Aryal M, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(48):E10281-E10290.
PMID: 29133392
Cavitation-facilitated microbubble-mediated focused ultrasound therapy is a promising method of drug delivery across the blood-brain barrier (BBB) for treating many neurological disorders. Unlike ultrasound thermal therapies, during which magnetic resonance...
10.
Aryal M, Fischer K, Gentile C, Gitto S, Zhang Y, McDannold N
PLoS One
. 2017 Jan;
12(1):e0166061.
PMID: 28045902
Many blood-borne substances attempting to pass through the luminal membrane of brain endothelial cells are acted upon by a variety of metabolizing enzymes or are actively expelled back into the...