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Motti Gerlic

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Articles 58
Citations 2994
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Recent Articles
1.
Levy O, Altaras A, Binyamini L, Sagi-Assif O, Izraely S, Cooks T, et al.
Cancers (Basel) . 2024 Nov; 16(22). PMID: 39594759
: In this study, for the first time, we examined and compared the sensitivity of four patient-derived cutaneous melanoma cell lines to alpha radiation in vitro and analyzed it in...
2.
Mass S, Cohen H, Podicheti R, Rusch D, Gerlic M, Ushijima B, et al.
PLoS Biol . 2024 Sep; 22(9):e3002734. PMID: 39226241
Vibrio coralliilyticus is a pathogen of coral and shellfish, leading to devastating economic and ecological consequences worldwide. Although rising ocean temperatures correlate with increased V. coralliilyticus pathogenicity, the specific molecular...
3.
Zhu Y, Speir M, Tan Z, Lee J, Nowell C, Chen A, et al.
Sci Adv . 2023 Dec; 9(51):eadj1397. PMID: 38117877
Neutrophil extracellular traps (NETs) not only counteract bacterial and fungal pathogens but can also promote thrombosis, autoimmunity, and sterile inflammation. The presence of citrullinated histones, generated by the peptidylarginine deiminase...
4.
Birk-Bachar M, Cohen H, Sofrin-Drucker E, Kropach-Gilad N, Orenstein N, Lidzbarsky G, et al.
Arthritis Rheumatol . 2023 Sep; 76(3):444-454. PMID: 37738164
Objective: Cryopyrin-associated periodic syndromes (CAPS), also known as NLRP3-associated autoinflammatory diseases, are a spectrum of rare autoinflammatory diseases caused by gain-of-function variants in the NLRP3 gene, resulting in inflammasome hyperactivation...
5.
Cohen H, Fridman C, Gerlic M, Salomon D
Microbiol Spectr . 2023 Jun; 11(4):e0109323. PMID: 37310285
Bacteria belonging to the genus include many known and emerging pathogens. Horizontal gene transfer of pathogenicity islands is a major contributor to the emergence of new pathogenic strains. Here, we...
6.
Vitale I, Pietrocola F, Guilbaud E, Aaronson S, Abrams J, Adam D, et al.
Cell Death Differ . 2023 Apr; 30(5):1097-1154. PMID: 37100955
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have...
7.
Bader G, Itan M, Edry-Botzer L, Cohen H, Haskin O, Mozer-Glassberg Y, et al.
Front Immunol . 2023 Apr; 14:1131965. PMID: 37051242
Protective immunity against COVID-19 is orchestrated by an intricate network of innate and adaptive anti-viral immune responses. Several vaccines have been rapidly developed to combat the destructive effects of COVID-19,...
8.
Dolitzky A, Hazut I, Avlas S, Grisaru-Tal S, Itan M, Zaffran I, et al.
Front Immunol . 2022 Nov; 13:1041660. PMID: 36389786
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis, host defense and cancer. Although eosinophils have been studied mostly...
9.
Cohen H, Baram N, Fridman C, Edry-Botzer L, Salomon D, Gerlic M
Elife . 2022 Sep; 11. PMID: 36155655
The type VI secretion system (T6SS) is used by bacteria to deliver toxic effectors directly into target cells. Most T6SSs mediate antibacterial activities, whereas the potential anti-eukaryotic role of T6SS...
10.
Shlomovitz I, Erlich Z, Arad G, Edry-Botzer L, Zargarian S, Cohen H, et al.
Cell Death Dis . 2021 Nov; 12(11):1059. PMID: 34750357
Necroptosis is a regulated and inflammatory form of cell death. We, and others, have previously reported that necroptotic cells release extracellular vesicles (EVs). We have found that necroptotic EVs are...