Motoki Kuhara
Overview
Explore the profile of Motoki Kuhara including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
190
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0
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Recent Articles
1.
Nishibata Y, Matsuzawa S, Satomura Y, Ohtsuka T, Kuhara M, Masuda S, et al.
Pathol Res Pract
. 2021 Nov;
228:153661.
PMID: 34749213
Anti-neutrophil cytoplasmic antibodies (ANCAs) are autoantibodies that recognize neutrophil cytoplasmic antigens. The major ANCA antigens are myeloperoxidase and proteinase 3. Necrotizing small vessel vasculitis accompanied by ANCA production is called...
2.
Hiroi S, Kuhara M, Kishi Y, Ono K, Matsuzawa S, Yamamoto N, et al.
Immunobiology
. 2017 Nov;
223(3):319-326.
PMID: 29107382
Influenza virus causes acute respiratory infection in humans, and is a major public health concern globally. Antibodies play a central role in host protection against influenza virus. We isolated human...
3.
Omokoko M, Pambudi S, Phanthanawiboon S, Masrinoul P, Setthapramote C, Sasaki T, et al.
Am J Trop Med Hyg
. 2014 Apr;
91(1):146-55.
PMID: 24778195
The immune response to dengue virus (DENV) infection generates high levels of antibodies (Abs) against the DENV non-structural protein 1 (NS1), particularly in cases of secondary infection. Therefore, anti-NS1 Abs...
4.
Pitaksajjakul P, Benjathummarak S, Pipattanaboon C, Wongwit W, Okabayashi T, Kuhara M, et al.
Biochem Biophys Res Commun
. 2014 Mar;
446(2):475-80.
PMID: 24637211
Dengue virus (DENV), a re-emerging virus, constitutes the largest vector-borne disease virus, with 50-100 million cases reported every year. Although DENV infection induces lifelong immunity against viruses of the same...
5.
Yasugi M, Kubota-Koketsu R, Yamashita A, Kawashita N, Du A, Misaki R, et al.
PLoS One
. 2013 Oct;
8(10):e77892.
PMID: 24147093
The swine-origin pandemic A(H1N1)2009 virus, A(H1N1)pdm09, is still circulating in parts of the human population. To monitor variants that may escape from vaccination specificity, antigenic characterization of circulating viruses is...
6.
Yasugi M, Kubota-Koketsu R, Yamashita A, Kawashita N, Du A, Sasaki T, et al.
PLoS Pathog
. 2013 Feb;
9(2):e1003150.
PMID: 23408886
Influenza virus has the ability to evade host immune surveillance through rapid viral genetic drift and reassortment; therefore, it remains a continuous public health threat. The development of vaccines producing...
7.
Setthapramote C, Sasaki T, Puiprom O, Limkittikul K, Pitaksajjakul P, Pipattanaboon C, et al.
Biochem Biophys Res Commun
. 2012 Jun;
423(4):867-72.
PMID: 22713454
The global spread of the four dengue virus serotypes (DENV-1 to -4) has made this virus a major and growing public health concern. Generally, pre-existing neutralizing antibodies derived from primary...
8.
Kurisaki T, Masuda A, Nakagiri S, Hayata Y, Kuhara M, Kishi Y, et al.
J Muscle Res Cell Motil
. 2011 May;
32(1):31-8.
PMID: 21597958
We established a novel monoclonal antibody, Yaksa that is specific to a subpopulation of myogenic cells. The Yaksa antigen is not expressed on the surface of growing myoblasts but only...
9.
Sun-Wada G, Tabata H, Kuhara M, Kitahara I, Takashima Y, Wada Y
Hybridoma (Larchmt)
. 2011 May;
30(2):199-203.
PMID: 21529295
The vacuolar-type proton pump ATPase (V-ATPase) plays several pivotal roles in the acidification of diverse intracellular compartments and the extracellular environment. The a subunit isoforms a1, a2, and a3, constituting...
10.
Kubota-Koketsu R, Mizuta H, Oshita M, Ideno S, Yunoki M, Kuhara M, et al.
Biochem Biophys Res Commun
. 2009 Jul;
387(1):180-5.
PMID: 19580789
Human monoclonal antibodies (HuMAbs) prepared from patients with viral infections could provide information on human epitopes important for the development of vaccines as well as potential therapeutic applications. Through the...