Moritz Widmaier
Overview
Explore the profile of Moritz Widmaier including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
612
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0
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Recent Articles
1.
Widmaier M, Wiestler T, Walker J, Barker C, Scott M, Sekhavati F, et al.
Mod Pathol
. 2019 Sep;
33(3):380-390.
PMID: 31527709
Tumor programmed cell death ligand-1 (PD-L1) expression is a key biomarker to identify patients with non-small cell lung cancer who may have an enhanced response to anti-programmed cell death-1 (PD-1)/PD-L1...
2.
Althammer S, Tan T, Spitzmuller A, Rognoni L, Wiestler T, Herz T, et al.
J Immunother Cancer
. 2019 May;
7(1):121.
PMID: 31060602
Background: Immune checkpoint therapies (ICTs) targeting the programmed cell death-1 (PD1)/programmed cell death ligand-1 (PD-L1) pathway have improved outcomes for patients with non-small cell lung cancer (NSCLC), particularly those with...
3.
Steele K, Tan T, Korn R, DaCosta K, Brown C, Kuziora M, et al.
J Immunother Cancer
. 2018 Mar;
6(1):20.
PMID: 29510739
Background: Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic,...
4.
Theodosiou M, Widmaier M, Bottcher R, Rognoni E, Veelders M, Bharadwaj M, et al.
Elife
. 2016 Jan;
5:e10130.
PMID: 26821125
Integrins require an activation step prior to ligand binding and signaling. How talin and kindlin contribute to these events in non-hematopoietic cells is poorly understood. Here we report that fibroblasts...
5.
Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, et al.
Nat Med
. 2014 Apr;
20(4):350-9.
PMID: 24681597
Kindlin-1 is an integrin tail binding protein that controls integrin activation. Mutations in the FERMT-1 gene, which encodes for Kindlin-1, lead to Kindler syndrome in man, which is characterized by...
6.
Widmaier M, Rognoni E, Radovanac K, Azimifar S, Fassler R
J Cell Sci
. 2012 May;
125(Pt 8):1839-43.
PMID: 22637643
No abstract available.
7.
Bottcher R, Stremmel C, Meves A, Meyer H, Widmaier M, Tseng H, et al.
Nat Cell Biol
. 2012 May;
14(6):584-92.
PMID: 22561348
Integrin functions are controlled by regulating their affinity for ligand, and by the efficient recycling of intact integrins through endosomes. Here we demonstrate that the Kindlin-binding site in the β1-integrin...
8.
Ussar S, Moser M, Widmaier M, Rognoni E, Harrer C, Genzel-Boroviczeny O, et al.
PLoS Genet
. 2008 Dec;
4(12):e1000289.
PMID: 19057668
Kindler Syndrome (KS), characterized by transient skin blistering followed by abnormal pigmentation, skin atrophy, and skin cancer, is caused by mutations in the FERMT1 gene. Although a few KS patients...