Morgane Boone
Overview
Explore the profile of Morgane Boone including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
732
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Recent Articles
1.
Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P
Elife
. 2024 Oct;
13.
PMID: 39361021
No abstract available.
2.
Boone M, Zappa F
Front Cell Dev Biol
. 2023 Dec;
11:1271141.
PMID: 38143923
The Integrated Stress Response (ISR) is an essential homeostatic signaling network that controls the cell's biosynthetic capacity. Four ISR sensor kinases detect multiple stressors and relay this information to downstream...
3.
Boone M, Ramasamy P, Zuallaert J, Bouwmeester R, Van Moer B, Maddelein D, et al.
Nat Commun
. 2023 Feb;
14(1):1072.
PMID: 36828852
No abstract available.
4.
Boone M, Wang L, Lawrence R, Frost A, Walter P, Schoof M
Elife
. 2022 Apr;
11.
PMID: 35416150
In eukaryotic cells, stressors reprogram the cellular proteome by activating the integrated stress response (ISR). In its canonical form, stress-sensing kinases phosphorylate the eukaryotic translation initiation factor eIF2 (eIF2-P), which...
5.
Schoof M, Wang L, Cogan J, Lawrence R, Boone M, Wuerth J, et al.
Nat Commun
. 2021 Dec;
12(1):7103.
PMID: 34876554
Viral infection triggers activation of the integrated stress response (ISR). In response to viral double-stranded RNA (dsRNA), RNA-activated protein kinase (PKR) phosphorylates the translation initiation factor eIF2, converting it from...
6.
Boone M, Ramasamy P, Zuallaert J, Bouwmeester R, Van Moer B, Maddelein D, et al.
Nat Commun
. 2021 Nov;
12(1):6414.
PMID: 34741024
While transcriptome- and proteome-wide technologies to assess processes in protein biogenesis are now widely available, we still lack global approaches to assay post-ribosomal biogenesis events, in particular those occurring in...
7.
Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P
Elife
. 2021 Mar;
10.
PMID: 33688831
The integrated stress response (ISR) is activated by phosphorylation of the translation initiation factor eIF2 in response to various stress conditions. Phosphorylated eIF2 (eIF2-P) inhibits eIF2's nucleotide exchange factor eIF2B,...
8.
Ramundo S, Asakura Y, Salome P, Strenkert D, Boone M, Mackinder L, et al.
Proc Natl Acad Sci U S A
. 2020 Dec;
117(51):32739-32749.
PMID: 33273113
In photosynthetic eukaryotes, thousands of proteins are translated in the cytosol and imported into the chloroplast through the concerted action of two translocons-termed TOC and TIC-located in the outer and...
9.
Krukowski K, Nolan A, Frias E, Boone M, Ureta G, Grue K, et al.
Elife
. 2020 Dec;
9.
PMID: 33258451
With increased life expectancy, age-associated cognitive decline becomes a growing concern, even in the absence of recognizable neurodegenerative disease. The integrated stress response (ISR) is activated during aging and contributes...
10.
Schoof M, Faust B, Saunders R, Sangwan S, Rezelj V, Hoppe N, et al.
Science
. 2020 Nov;
370(6523):1473-1479.
PMID: 33154106
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters host cells via an interaction between its Spike protein and the host cell receptor angiotensin-converting enzyme 2 (ACE2). By screening...