Moran Golan
Overview
Explore the profile of Moran Golan including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
127
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0
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Recent Articles
1.
Tsoref O, Tyomkin D, Amit U, Landa N, Cohen-Rosenboim O, Kain D, et al.
J Control Release
. 2018 Aug;
288:136-147.
PMID: 30165141
Endothelial activation with up-regulation of E-selectin adhesion molecules mediates leukocyte rolling along the vascular wall and controls inflammation in many diseases including atherosclerosis and heart failure. Therefore, we aimed to...
2.
Golan M, Feinshtein V, David A
Eur J Pharm Biopharm
. 2016 Oct;
109:103-112.
PMID: 27702685
The key for successful gene silencing is to design a safe and efficient siRNA delivery system for the transfer of therapeutic nucleic acids into the target cells. Here, we describe...
3.
Assessing the therapeutic efficacy of VEGFR-1-targeted polymer drug conjugates in mouse tumor models
Shamay Y, Golan M, Tyomkin D, David A
J Control Release
. 2016 Mar;
229:192-199.
PMID: 27001892
Polymer-drug conjugates that can actively target the tumor vasculature have emerged as an attractive technology for improving the therapeutic efficacy of cytotoxic drugs. We have recently provided, for the first...
4.
Golan M, Feinshtein V, Polyak D, Scomparin A, Satchi-Fainaro R, David A
Bioconjug Chem
. 2016 Mar;
27(4):947-60.
PMID: 26974863
In recent years, siRNA technology has emerged as a promising strategy for gene silencing in cancer therapy. We have designed novel CD44-targeted polyion complexes (PICs) composed of poly(ethylene glycol)-block-polyethylenimine (PEG-b-PEI)...
5.
Shamay Y, Raviv L, Golan M, Voronov E, Apte R, David A
J Control Release
. 2015 Aug;
217:102-12.
PMID: 26297207
There is currently no effective means to prevent or control metastatic dissemination of cancer cells. E-selectin, an adhesion molecule expressed exclusively on inflamed and angiogenic blood vessels, plays an important...
6.
Golani-Armon A, Golan M, Shamay Y, Raviv L, David A
Bioconjug Chem
. 2015 Jan;
26(2):213-24.
PMID: 25560976
Dendritic cells (DCs) are a family of specialized antigen presenting cells (APCs) that detect antigens and initiate a wide spectrum of immune responses against them. These characteristics make them promising...
7.
Kogan-Zviagin I, Shamay Y, Nissan A, Sella-Tavor O, Golan M, David A
J Control Release
. 2014 Jul;
192:182-91.
PMID: 25008468
There is increasing interest in the use of nanoparticle imaging probes for cancer diagnosis. However, various biological barriers limit the efficient delivery of nanoparticles to tumors following parenteral administration. We...
8.
Golan M, Schreiber G, Avissar S
Int J Neuropsychopharmacol
. 2013 May;
16(8):1745-54.
PMID: 23672745
β-Arrestins 1 and 2, cytosolic proteins known to mediate receptor desensitization, endocytosis and G protein-independent signalling, are post-translationally modified by ubiquitination regulating their ability to serve as adaptors and scaffolds....
9.
Golan M, Schreiber G, Avissar S
Int J Neuropsychopharmacol
. 2011 Jan;
14(10):1289-300.
PMID: 21223624
Glial cell line-derived neurotrophic factor (GDNF), essential for neuronal survival, plasticity and development, has been implicated in the mechanism of action of antidepressant drugs (ADs). β-arrestin1, a member of the...
10.
Schreiber G, Golan M, Avissar S
Drug News Perspect
. 2009 Dec;
22(8):467-80.
PMID: 20016856
Beta-arrestins uncouple G protein-coupled receptors (GPCRs) from G proteins and promote their internalization, leading to desensitization and downregulation and serving as negative regulators of GPCR signaling. beta-Arrestins also function as...