Monica Villa-Alvarez
Overview
Explore the profile of Monica Villa-Alvarez including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
249
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0
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Recent Articles
1.
Lorenzo-Herrero S, Sordo-Bahamonde C, Bretones G, Payer A, Gonzalez-Rodriguez A, Gonzalez-Garcia E, et al.
Front Immunol
. 2019 Nov;
10:2455.
PMID: 31681329
B-cell receptor (BCR)-dependent signaling is central for leukemia B-cell homeostasis, as underscored by the promising clinical results obtained in patients with chronic lymphocytic leukemia (CLL) treated with novel agents targeting...
2.
Gonzalez-Rodriguez A, Villa-Alvarez M, Sordo-Bahamonde C, Lorenzo-Herrero S, Gonzalez S
J Clin Med
. 2019 Oct;
8(10).
PMID: 31569769
Natural killer (NK) cells have the innate ability to kill cancer cells, however, tumor cells may acquire the capability of evading the immune response, thereby leading to malignancies. Restoring or...
3.
Villa-Alvarez M, Sordo-Bahamonde C, Lorenzo-Herrero S, Gonzalez-Rodriguez A, Payer A, Gonzalez-Garcia E, et al.
Front Immunol
. 2019 Jan;
9:2917.
PMID: 30619281
One of the cardinal features of chronic lymphocytic leukemia (CLL) is its association with a profound immunosuppression. NK cell function is markedly impaired in CLL patients, who show a significant...
4.
Villa-Alvarez M, Lorenzo-Herrero S, Gonzalez-Rodriguez A, Lopez-Soto A, Payer A, Gonzalez-Garcia E, et al.
Oncoimmunology
. 2017 Nov;
6(10):e1353856.
PMID: 29123965
Chronic lymphocytic leukemia (CLL) is associated with a profound dysregulation of the immune system. Loss of T cell function is frequently caused in cancer by sustained signaling of inhibitory receptors....
5.
Fernandez-Guizan A, Lopez-Soto A, Acebes-Huerta A, Huergo-Zapico L, Villa-Alvarez M, Nunez L, et al.
PLoS One
. 2015 Nov;
10(11):e0140786.
PMID: 26536461
Demycarosyl-3D-ß-D-digitoxosyl-mithramycin SK (DIG-MSK) is a recently isolated analogue of mithramycin A (MTA) that showed differences with MTA in the DNA binding strength and selectivity. These differences correlated with a better...
6.
Huergo-Zapico L, Acebes-Huerta A, Gonzalez-Rodriguez A, Contesti J, Gonzalez-Garcia E, Payer A, et al.
PLoS One
. 2014 Oct;
9(10):e108326.
PMID: 25286418
The immune system may mediate anti-tumor responses in chronic lymphocytic leukemia (CLL) which may affect disease progression and survival. In this study, we analyzed the immune characteristics of 99 consecutive...
7.
Huergo-Zapico L, Acebes-Huerta A, Lopez-Soto A, Villa-Alvarez M, Gonzalez-Rodriguez A, Gonzalez S
Front Immunol
. 2014 Apr;
5:106.
PMID: 24711808
NKG2D is an activating receptor expressed by NK and T cells primarily involved in the elimination of transformed and infected cells. NKG2D ligands are self-proteins restrictedly expressed in healthy tissues,...
8.
Lopez-Soto A, Huergo-Zapico L, Acebes-Huerta A, Villa-Alvarez M, Gonzalez S
Int J Cancer
. 2014 Mar;
136(8):1741-50.
PMID: 24615398
The immune system is able to detect and eliminate transformed cells. The activating receptor NKG2D is particularly relevant for cancer immunosurveillance. NKG2D ligand expression renders tumor cells more susceptible to...
9.
Gonzalez-Rodriguez A, Payer A, Acebes-Huerta A, Huergo-Zapico L, Villa-Alvarez M, Gonzalez-Garcia E, et al.
Biomed Res Int
. 2013 Oct;
2013:932010.
PMID: 24163824
Lenalidomide is an oral immunomodulatory drug used in multiple myeloma and myelodysplastic syndrome and most recently it has shown to be effective in the treatment of various lymphoproliferative disorders such...