Monica P McNerney
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Explore the profile of Monica P McNerney including associated specialties, affiliations and a list of published articles.
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12
Citations
195
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Recent Articles
1.
McSweeney M, Patterson A, Loeffler K, Cuellar Lelo de Larrea R, McNerney M, Kane R, et al.
Sci Adv
. 2025 Feb;
11(8):eado6280.
PMID: 39982986
Conventional laboratory protein detection techniques are not suitable for point-of-care (POC) use because they require expensive equipment and laborious protocols, and existing POC assays suffer from long development timescales. Here,...
2.
McSweeney M, Patterson A, Loeffler K, Cuellar Lelo de Larrea R, McNerney M, Kane R, et al.
bioRxiv
. 2024 Jul;
PMID: 39071415
Conventional laboratory protein detection techniques are not suitable for point-of-care (POC) use because they require expensive equipment and laborious protocols, and existing POC assays suffer from long development timescales. Here,...
3.
Zhang Y, Kojima T, Kim G, McNerney M, Takayama S, Styczynski M
Nat Commun
. 2021 Sep;
12(1):5724.
PMID: 34588445
Simultaneous detection of multiple analytes from a single sample (multiplexing), particularly when done at the point of need, can guide complex decision-making without increasing the required sample volume or cost...
4.
McNerney M, Doiron K, Ng T, Chang T, Silver P
Nat Rev Genet
. 2021 Jul;
22(11):730-746.
PMID: 34234299
Synthetic biology seeks to redesign biological systems to perform novel functions in a predictable manner. Recent advances in bacterial and mammalian cell engineering include the development of cells that function...
5.
Miguez A, McNerney M, Styczynski M
Ind Eng Chem Res
. 2020 Feb;
58(50):22472-22482.
PMID: 32063671
Biotechnology has transformed the production of various chemicals and pharmaceuticals due to its efficient and selective processes, but it is inherently limited by its use of live cells as "biocatalysts."...
6.
McNerney M, Piorino F, Michel C, Styczynski M
ACS Synth Biol
. 2020 Jan;
9(2):402-411.
PMID: 31977200
Cell-free systems provide a versatile platform for the development of low-cost, easy-to-use sensors for diverse analytes. However, sensor affinity dictates response sensitivity, and improving binding affinity can be challenging. Here,...
7.
McNerney M, Michel C, Kishore K, Standeven J, Styczynski M
Nat Commun
. 2019 Dec;
10(1):5514.
PMID: 31797936
Bacterial biosensors can enable programmable, selective chemical production, but difficulties incorporating metabolic pathways into complex sensor circuits have limited their development and applications. Here we overcome these challenges and present...
8.
McNerney M, Zhang Y, Steppe P, Silverman A, Jewett M, Styczynski M
Sci Adv
. 2019 Oct;
5(9):eaax4473.
PMID: 31579825
Easy-to-perform, relatively inexpensive blood diagnostics have transformed at-home healthcare for some patients, but they require analytical equipment and are not easily adapted to measuring other biomarkers. The requirement for reliable...
9.
Miguez A, McNerney M, Styczynski M
Front Microbiol
. 2018 May;
9:760.
PMID: 29774011
Using cells as microbial factories enables highly specific production of chemicals with many advantages over chemical syntheses. A number of exciting new applications of this approach are in the area...
10.
McNerney M, Styczynski M
Wiley Interdiscip Rev Syst Biol Med
. 2017 Sep;
10(2).
PMID: 28960879
Small molecules have many important roles across the tree of life: they regulate processes from metabolism to transcription, they enable signaling within and between species, and they serve as the...