Monica M Montano
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Explore the profile of Monica M Montano including associated specialties, affiliations and a list of published articles.
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31
Citations
550
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Recent Articles
1.
Sharma V, Joshi J, Yeh I, Doughman Y, Blankenberg D, Wald D, et al.
Front Oncol
. 2022 Apr;
12:824594.
PMID: 35402240
DNA methylation, catalyzed by DNA methyltransferase (DNMT), is a well-characterized epigenetic modification in cancer cells. In particular, promoter hypermethylation of and results in loss of expression on Androgen Receptor (AR)...
2.
Mozar F, Sharma V, Gorityala S, Albert J, Xu Y, Montano M
Endocrinology
. 2021 Dec;
163(1).
PMID: 34864989
We have previously reported that hexamethylene bis-acetamide inducible protein 1 (HEXIM1) inhibits the activity of ligand-bound estrogen receptor α (ERα) and the androgen receptor (AR) by disrupting the interaction between...
3.
Sha Z, Montano M, Rochon K, Mears J, Deredge D, Wintrode P, et al.
Arch Biochem Biophys
. 2021 Jul;
710:108983.
PMID: 34228963
Lon is an ATP-dependent protease belonging to the "ATPase associated with diverse cellular activities" (AAA+) protein family. In humans, Lon is translated as a precursor and imported into the mitochondria...
4.
Sharma V, Montano M
Sci Rep
. 2020 Dec;
10(1):21015.
PMID: 33273553
We have been studying the role of Hexamethylene bisacetamide (HMBA) Induced Protein 1 (HEXIM1) as a tumor suppressor whose expression is decreased in breast and prostate cancer. The anti-cancer actions...
5.
Montano M, Yeh I, Chen Y, Hernandez C, Kiselar J, Fuente M, et al.
Breast Cancer Res
. 2019 Dec;
21(1):138.
PMID: 31805991
Background: The tumor suppressor actions of hexamethylene bis-acetamide (HMBA)-inducible protein 1 (HEXIM1) in the breast, prostate, melanomas, and AML have been reported by our group and others. Increased HEXIM1 expression...
6.
Yeh I, Esakov E, Lathia J, Miyagi M, Reizes O, Montano M
Sci Rep
. 2019 Nov;
9(1):17663.
PMID: 31776402
Epigenetic modifications are known to play critical roles in the expression of genes related to differentiation and dedifferentiation. Histone lysine demethylase KDM5B (PLU-1) catalyzes the demethylation of histone H3 on...
7.
Abd El-Hafeez A, Khalifa H, Mahdy E, Sharma V, Hosoi T, Ghosh P, et al.
Pharmacol Rep
. 2019 Mar;
71(2):289-298.
PMID: 30826569
Background: Nor-wogonin, a polyhydroxy flavone, has been shown to possess antitumor activity. However, the mechanisms responsible for its antitumor activity are poorly studied. Herein, we investigated the mechanisms of nor-wogonin...
8.
Fathi M, Abd El-Hafeez A, Abdelhamid D, Abbas S, Montano M, Abdel-Aziz M
Bioorg Chem
. 2018 Dec;
84:150-163.
PMID: 30502626
A new series of 1,3,4-oxadiazole/chalcone hybrids was designed, synthesized, identified with different spectroscopic techniques and biologically evaluated as inhibitors of EGFR, Src, and IL-6. The synthesized compounds showed promising anticancer...
9.
Abbas S, Abd El-Hafeez A, Shoman M, Montano M, Hassan H
Bioorg Chem
. 2018 Nov;
82:360-377.
PMID: 30428415
A series of quinoline-chalcone hybrids was designed as potential anti-cancer agents, synthesized and evaluated. Different cytotoxic assays revealed that compounds experienced promising activity. Compounds 9i and 9j were the most...
10.
Gorityala S, Yang S, Montano M, Xu Y
J Chromatogr B Analyt Technol Biomed Life Sci
. 2018 May;
1090:22-35.
PMID: 29778874
Androgens play a vital role in prostate cancer development, and their elimination and blockade are essential in the disease management. DHT is the key ligand for androgen receptor (AR) in...