Mohsen Moslem
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Explore the profile of Mohsen Moslem including associated specialties, affiliations and a list of published articles.
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16
Citations
270
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Recent Articles
1.
Jain S, Voulgaris D, Thongkorn S, Hesen R, Hagg A, Moslem M, et al.
Adv Sci (Weinh)
. 2024 Apr;
11(25):e2401859.
PMID: 38655836
The clinical translation of induced pluripotent stem cells (iPSCs) holds great potential for personalized therapeutics. However, one of the main obstacles is that the current workflow to generate iPSCs is...
2.
Mastropasqua F, Oksanen M, Soldini C, Alatar S, Arora A, Ballarino R, et al.
Biol Open
. 2023 Oct;
12(10).
PMID: 37815090
Genetic variants affecting Heterogeneous Nuclear Ribonucleoprotein U (HNRNPU) have been identified in several neurodevelopmental disorders (NDDs). HNRNPU is widely expressed in the human brain and shows the highest postnatal expression...
3.
Schuy J, Eisfeldt J, Pettersson M, Shahrokhshahi N, Moslem M, Nilsson D, et al.
Front Genet
. 2022 Feb;
12:803683.
PMID: 35186010
Induced pluripotent stem cells (iPSCs) from patients are an attractive disease model to study tissues with poor accessibility such as the brain. Using this approach, we and others have shown...
4.
Rostami J, Mothes T, Kolahdouzan M, Eriksson O, Moslem M, Bergstrom J, et al.
J Neuroinflammation
. 2021 Jun;
18(1):124.
PMID: 34082772
Background: Alzheimer's disease (AD) and Parkinson's disease (PD) are characterized by brain accumulation of aggregated amyloid-beta (Aβ) and alpha-synuclein (αSYN), respectively. In order to develop effective therapies, it is crucial...
5.
Susanto E, Navarro A, Zhou L, Sundstrom A, van Bree N, Stantic M, et al.
Proc Natl Acad Sci U S A
. 2020 Aug;
117(33):20127-20138.
PMID: 32747535
Medulloblastoma is the most common malignant brain tumor in children. Here we describe a medulloblastoma model using Induced pluripotent stem (iPS) cell-derived human neuroepithelial stem (NES) cells generated from a...
6.
Kvarnung M, Shahsavani M, Taylan F, Moslem M, Breeuwsma N, Laan L, et al.
Front Genet
. 2019 Oct;
10:896.
PMID: 31608123
The etiology of hereditary ataxia syndromes is heterogeneous, and the mechanisms underlying these disorders are often unknown. Here, we utilized exome sequencing in two siblings with progressive ataxia and muscular...
7.
Lam M, Moslem M, Bryois J, Pronk R, Uhlin E, Dehnisch Ellstrom I, et al.
Exp Cell Res
. 2019 Jul;
383(1):111469.
PMID: 31302032
We generated human iPS derived neural stem cells and differentiated cells from healthy control individuals and an individual with autism spectrum disorder carrying bi-allelic NRXN1-alpha deletion. We investigated the expression...
8.
Moslem M, Olive J, Falk A
Schizophr Res
. 2018 Dec;
210:3-12.
PMID: 30587427
Schizophrenia is a complex disorder with clinical manifestations in early adulthood. However, it may start with disruption of brain development caused by genetic or environmental factors, or both. Early deteriorating...
9.
Moslem M, Eggenschwiler R, Wichmann C, Buhmann R, Cantz T, Henschler R
Stem Cells Int
. 2017 Feb;
2017:7316354.
PMID: 28163724
Kindlin-2 is a multidomain intracellular protein that can be recruited to -integrin domains to activate signaling, initiate transcriptional programs, and bind to E-cadherin. To explore its involvement in cell fate...
10.
Eggenschwiler R, Moslem M, Fraguas M, Galla M, Papp O, Naujock M, et al.
Sci Rep
. 2016 Dec;
6:38198.
PMID: 27910942
Homology directed repair (HDR)-based genome editing via selectable long flanking arm donors can be hampered by local transgene silencing at transcriptionally silent loci. Here, we report efficient bi-allelic modification of...