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» Authors » Mohd Shahbaaz

Mohd Shahbaaz

Explore the profile of Mohd Shahbaaz including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 49
Citations 378
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Biology
Top 10 Co-Authors
Md Imtaiyaz Hassan
Faizan Ahmad
Krishna Bisetty
Asimul Islam
Magda H Abdellattif
Alan Christoffels
Anas Shamsi
Parvez Khan
Mostafa A Hussien
Maria Grishina
Published In
J Biomol Struct Dyn
PLoS One
Front Mol Biosci
Molecules
Comput Biol Chem
Affiliations
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Recent Articles
1.
Cucumis melo var. momordica as a Potent Antidiabetic, Antioxidant and Possible Anticovid Alternative: Investigation through Experimental and Computational Methods
Yadav J, Grishina M, Shahbaaz M, Mukerjee A, Singh S, Pathak P
Chem Biodivers . 2022 Aug; 19(9):e202200200. PMID: 35950335
Diabetes mellitus is a typical life threatening of disease, which generate due to the dysfunction of β cells of pancreas. In 2014, WHO stated that 422 million people were infected...
2.
Multistage antiplasmodial activity of hydroxyethylamine compounds, and evaluations
Sharma N, Gupta Y, Bansal M, Singh S, Pathak P, Shahbaaz M, et al.
RSC Adv . 2022 Jun; 10(58):35516-35530. PMID: 35686031
Malaria, a global threat to the human population, remains a challenge partly due to the fast-growing drug-resistant strains of species. New therapeutics acting against the pathogenic asexual and sexual stages,...
3.
Drug repurposing through virtual screening and in vitro validation identifies tigecycline as a novel putative HCV polymerase inhibitor
ElHefnawi M, Jo E, Tolba M, Fares M, Yang J, Shahbaaz M, et al.
Virology . 2022 Mar; 570:9-17. PMID: 35338891
The repurposing of marketed drugs for new indications is an elegant strategy to quickly and cost-efficiently address unmet medical needs. The hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) has...
4.
Repurposing Based Identification of Novel Inhibitors against MmpS5-MmpL5 Efflux Pump of : A Combined In Silico and In Vitro Study
Shahbaaz M, Maslov D, Vatlin A, Danilenko V, Grishina M, Christoffels A
Biomedicines . 2022 Feb; 10(2). PMID: 35203542
In the current era of a pandemic, infections of COVID-19 and Tuberculosis (TB) enhance the detrimental effects of both diseases in suffering individuals. The resistance mechanisms evolving in are limiting...
5.
In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c)
Cloete R, Shahbaaz M, Grobbelaar M, Sampson S, Christoffels A
PLoS One . 2021 Nov; 16(11):e0259348. PMID: 34727137
Nicotinamide-nucleotide adenylyl transferase (Rv2421c) was selected as a potential drug target, because it has been shown, in vitro, to be essential for Mycobacterium tuberculosis growth. It is conserved between mycobacterium...
6.
Peptides-based therapeutics: Emerging potential therapeutic agents for COVID-19
Shah J, Guo G, Krishnan A, Ramesh M, Kumar Katari N, Shahbaaz M, et al.
Therapie . 2021 Oct; 77(3):319-328. PMID: 34689960
SARS-CoV-2 is a positive-sense RNA virus and it is the causative agent of the global COVID-19 outbreak. COVID-19 is similar to the previous outbreaks for instance SARS in 2002-2003 and...
7.
Computational Approaches for the Design of Novel Anticancer Compounds Based on Pyrazolo[3,4-d]pyrimidine Derivatives as TRAP1 Inhibitor
Ali A, Abdellattif M, Ali A, AbuAli O, Shahbaaz M, Ahsan M, et al.
Molecules . 2021 Oct; 26(19). PMID: 34641473
In the present in-silico study, various computational techniques were applied to determine potent compounds against TRAP1 kinase. The pharmacophore hypothesis DHHRR_1 consists of important features required for activity. The 3D...
8.
Oxazinethione Derivatives as a Precursor to Pyrazolone and Pyrimidine Derivatives: Synthesis, Biological Activities, Molecular Modeling, ADME, and Molecular Dynamics Studies
Abdellattif M, Shahbaaz M, Arief M, Hussien M
Molecules . 2021 Sep; 26(18). PMID: 34576953
In this study, we used oxazinethione as a perfect precursor to synthesize new pyrimidine and pyrazole derivatives with potent biological activities. Biological activities were determined for all compounds against ....
9.
Corrigendum: Synthesis and Cytotoxic Activity of Novel Indole Derivatives and Their Screening on Spike Glycoprotein of SARS-CoV-2
Gobinath P, Packialakshmi P, Vijayakumar K, Abdellattif M, Shahbaaz M, Idhayadhulla A, et al.
Front Mol Biosci . 2021 Aug; 8:716238. PMID: 34422908
[This corrects the article DOI: 10.3389/fmolb.2021.637989.].
10.
Transcriptomic Profile of in Response to an Imidazo[1,2-][1,2,4,5]tetrazine Reveals Its Possible Impact on Iron Metabolism
Vatlin A, Shitikov E, Shahbaaz M, Bespiatykh D, Klimina K, Christoffels A, et al.
Front Microbiol . 2021 Aug; 12:724042. PMID: 34421882
Tuberculosis (TB), caused by the complex bacteria, is one of the most pressing health problems. The development of new drugs and new therapeutic regimens effective against the pathogen is one...