Mohammed Najeeb Al Hallak
Overview
Explore the profile of Mohammed Najeeb Al Hallak including associated specialties, affiliations and a list of published articles.
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14
Citations
404
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Recent Articles
1.
Hadid T, Biedny A, Mamdani H, Azmi A, Kim S, Jang H, et al.
Ther Adv Vaccines Immunother
. 2024 Dec;
12:25151355241309095.
PMID: 39737331
Background: Cannabis (CAN) use has risen significantly over the last few decades. CAN has potent immunosuppressive properties, which could antagonize the effect of immunotherapy (IO). The impact of CAN use...
2.
Kim D, Schram A, Hollebecque A, Nishino K, Macarulla T, Rha S, et al.
Future Oncol
. 2024 Feb;
20(16):1057-1067.
PMID: 38348690
Neuregulin 1 () fusions are oncogenic drivers that have been detected in non-small-cell lung cancer (NSCLC), pancreatic ductal adenocarcinoma (PDAC) and other solid tumors. fusions are rare, occurring in less...
3.
Cobani E, Al Hallak M, Shields A, Maier J, Kelly T, Naidoo N, et al.
J Gastrointest Cancer
. 2024 Jan;
55(2):519-533.
PMID: 38180678
Purpose: Gastric cancer is the 5th most common malignancy worldwide. As early detection increases and treatments for gastric cancer improve, the number of gastric cancer survivors grows. Methods: Here, we...
4.
Almujarkesh M, Damughatla A, Bathla J, Sugg K, LaBuda D, Alkassis S, et al.
Gastroenterology Res
. 2023 Nov;
16(5):276-279.
PMID: 37937226
Primary squamous cell carcinoma (SCC) of the liver is quite rare, and to our knowledge, very few cases have been reported in the literature. The exact pathogenesis of the disease...
5.
Khan H, Nagasaka M, Aboukameel A, Alkhalili O, Uddin M, Bannoura S, et al.
Mol Cancer Ther
. 2023 Sep;
22(12):1422-1433.
PMID: 37703579
KRASG12C inhibitors, such as sotorasib and adagrasib, have revolutionized cancer treatment for patients with KRASG12C-mutant tumors. However, patients receiving these agents as monotherapy often develop drug resistance. To address this...
6.
Khan H, Kamgar M, Aboukameel A, Bannoura S, Chung B, Li Y, et al.
Adv Radiat Oncol
. 2022 Dec;
8(1):101122.
PMID: 36479231
Purpose: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease. Novel and effective approaches to accomplish durable...
7.
Spotlight on Trastuzumab Deruxtecan (DS-8201,T-DXd) for Mutation Positive Non-Small Cell Lung Cancer
Azar I, Alkassis S, Fukui J, Alsawah F, Fedak K, Al Hallak M, et al.
Lung Cancer (Auckl)
. 2021 Oct;
12:103-114.
PMID: 34675733
Human epidermal growth factor receptor 2 () is a proto-oncogene that, when mutated or overexpressed, plays an important role in oncogenesis. The landscape of -positive breast cancer has changed dramatically...
8.
Nagasaka M, Asad M, Al Hallak M, Uddin M, Sukari A, Baca Y, et al.
Lung Cancer
. 2021 Sep;
160:92-98.
PMID: 34482103
Background: Nuclear protein transport is essential in guiding the traffic of important proteins and RNAs between the nucleus and cytoplasm. Export of proteins from the nucleus is mostly regulated by...
9.
Non-Coding RNAs in Pancreatic Cancer Diagnostics and Therapy: Focus on lncRNAs, circRNAs, and piRNAs
Li Y, Al Hallak M, Philip P, Azmi A, Mohammad R
Cancers (Basel)
. 2021 Aug;
13(16).
PMID: 34439315
Pancreatic cancer is an aggressive malignance with high mortality. The lack of early diagnosis and effective therapy contributes to the high mortality of this deadly disease. For a long time...
10.
Al-Share B, Alloghbi A, Al Hallak M, Uddin H, Azmi A, Mohammad R, et al.
Cancer Metastasis Rev
. 2021 Apr;
40(2):625-641.
PMID: 33876372
Gastrointestinal stromal tumors (GIST) are rare neoplasms arising from the interstitial cell of Cajal in the gastrointestinal tract. Two thirds of GIST in adult patients have c-Kit mutation and smaller...