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Mohammed M Alanazi

Explore the profile of Mohammed M Alanazi including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 112
Citations 645
Followers 0
Related Specialties
Chemistry
Biochemistry
Biology
Top 10 Co-Authors
Nawaf A Alsaif
Ahmad J Obaidullah
Ashwag S Alanazi
Hamad M Alkahtani
Sheikh F Ahmad
Ahmed Nadeem
Abdullah A Aldossari
Sabry M Attia
Saleh A Bakheet
Wajid Rehman
Published In
Molecules
Pharmaceuticals (Basel)
ACS Omega
Saudi Pharm J
Bioorg Chem
Affiliations
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Recent Articles
1.
Benzothiazole Derived Ether Hybrids as Potent Anti-Thymidine Phosphorylase Agents: Synthesis, In Vitro, and Computational Investigations
Usman M, Alam A, Zainab Z, Zainab , Khan M, Tuzun B, et al.
Chem Biodivers . 2025 Feb; :e202403385. PMID: 39946148
This work is based on the synthesis of new ether derivatives bearing benzothiazole (BTA) scaffold through multistep reaction process. Initially, BTA was prepared by refluxing 4-hydroxybenzaldehyde with aminothiophenol having sodium...
2.
An Investigation into the Synthesis and Characterization of Novel Tetrazole Derivatives for Application as Mild Steel Corrosion Inhibitors in a Solution of Hydrochloric Acid
Sghyar R, Rhazi Y, Aloui M, Lahyaoui M, Elmrayej H, Elmsellem H, et al.
ACS Omega . 2025 Jan; 10(2):2069-2080. PMID: 39866633
The objective of the study was to synthesize tetrazole molecules featuring nitro groups positioned at the para and meta locations. We aimed to assess their effectiveness in inhibiting corrosion of...
3.
Novel D-Ribofuranosyl Tetrazoles: Synthesis, Characterization, In Vitro Antimicrobial Activity, and Computational Studies
Sghyar R, Lahyaoui M, Rhazi Y, Aflak N, Moussaoui O, Chda A, et al.
ACS Omega . 2025 Jan; 10(2):2116-2129. PMID: 39866623
The goal of this study was to synthesize and evaluate new antimicrobial compounds. We specifically focused on the development of 2,5-disubstituted tetrazole derivatives containing the O-methyl-2,3-O-isopropylidene-(D)-ribofuranoside groups through N-alkylation reactions....
4.
Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations
Hdoufane I, Oubahmane M, Habibi Y, Delaite C, Alanazi M, Cherqaoui D
Sci Rep . 2025 Jan; 15(1):2748. PMID: 39838126
TMPRSS4, a transmembrane serine protease type II, is associated with various pathological illnesses. It has been found to activate SARS-CoV-2, enhance viral infection of human small-intestinal enterocytes and is overexpressed...
5.
Green Synthesis of Zinc Oxide Nanoparticles for Tetracycline Adsorption: Experimental Insights and DFT Study
Alshahateet S, Al-Trawneh S, Er-Rajy M, Zerrouk M, Azzaoui K, Al-Tawarh W, et al.
Plants (Basel) . 2024 Dec; 13(23). PMID: 39683179
An eco-friendly approach was used to fabricate zinc oxide nanoparticles (ZnO NPs) using thyme, L., leaf extract. The produced ZnO nanoparticles were characterized by XRD and SEM analysis. The ZnO...
6.
Cheminformatics-based design and biomedical applications of a new Hydroxyphenylcalix[4] resorcinarene as anti-cancer agent
Alshahateet S, Altarawneh R, Al-Trawneh S, Al-Saraireh Y, Al-Tawarh W, Abuawad K, et al.
Sci Rep . 2024 Dec; 14(1):30460. PMID: 39672820
The distinct conformational characteristics, functionality, affordability, low toxicity, and usefulness make calixarene-based compounds a promising treatment option for cancer. The aim of the present study is to synthesize a new...
7.
The Role of Dapagliflozin in the Modulation of Hypothermia and Renal Injury Caused by Septic Shock in Euglycemic and Hyperglycemic Rat Models
Alanazi W, Alharbi T, Bin Anzan K, Alyahiya M, El-Nagar D, Alanazi M, et al.
Curr Mol Pharmacol . 2024 Dec; 17:e18761429329635. PMID: 39670498
Background: Recent research has validated the efficacy of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in reducing glucose levels and exerting a nephroprotective role. Objective: This study aimed to examine the impact of...
8.
GC-MS Characterization and Bioactivity Study of Labill. (Myrtaceae) Essential Oils and Their Fractions: Antibacterial and Antioxidant Properties and Molecular Docking Modeling
Benlabchir A, Fikri-Benbrahim K, Moutawalli A, Alanazi M, Halmoune A, Benkhouili F, et al.
Pharmaceuticals (Basel) . 2024 Nov; 17(11). PMID: 39598461
Background/objectives: is a medicinal plant extensively used by the Moroccan population for treating a range of illnesses, especially respiratory conditions. Methods: This study aimed to assess the antioxidant and antibacterial...
9.
Synthesis and biological evaluation of diclofenac acid derivatives as potential lipoxygenase and α-glucosidase inhibitors
Sardar A, Abid O, Rehman W, Rasheed L, Alanazi M, Daud S, et al.
R Soc Open Sci . 2024 Nov; 11(11):240543. PMID: 39569345
Inflammation is a complex physiological response associated with the onset and progression of various disorders, including diabetes. In this study, we synthesized a series of diclofenac acid derivatives and evaluated...
10.
New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study
Rhazi Y, Sghyar R, Deak N, Es-Sounni B, Rossafi B, Soran A, et al.
Pharmaceuticals (Basel) . 2024 Oct; 17(10). PMID: 39459029
: This research centers on the development and spectroscopic characterization of new quinazolin-4(3H)-one-isoxazole derivatives (). The aim was to investigate the regioselectivity of the 1,3-dipolar cycloaddition involving arylnitriloxides and N-propargylquinazolin-4(3H)-one,...