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» Authors » Mohammad Jalalirad

Mohammad Jalalirad

Explore the profile of Mohammad Jalalirad including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 236
Followers 0
Related Specialties
Oncology
Biochemistry
Microbiology
Top 10 Co-Authors
Liewei Wang
Michael Laughrea
Ann Tuma
Jann Sarkaria
Minzhi Zhang
Tufia Haddad
James N Ingle
Jeffrey L Salisbury
Antonino B DAssoro
Luca Zammataro
Published In
Virology
Breast Cancer Res
Front Oncol
J Virol
Oncogene
Affiliations
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Recent Articles
1.
Blockade of tumor cell-intrinsic PD-L1 signaling enhances AURKA-targeted therapy in triple negative breast cancer
Takchi A, Zhang M, Jalalirad M, Ferre R, Shrestha R, Haddad T, et al.
Front Oncol . 2024 Jun; 14:1384277. PMID: 38873259
Triple negative breast cancer (TNBC) accounts for 15-20% of all breast cancers and mainly affects pre-menopausal and minority women. Because of the lack of ER, PR or HER2 expression in...
2.
Inhibition of triple‑negative breast cancer proliferation and motility by reactivating p53 and inhibiting overactivated Akt
Cao W, Shen R, Richard S, Liu Y, Jalalirad M, Cleary M, et al.
Oncol Rep . 2021 Dec; 47(2). PMID: 34958116
Mutations of p53 tumor suppressors occur more frequently in cancers at advanced stages or in more malignant cancer subtypes such as triple‑negative breast cancer. Thus, restoration of p53 tumor suppressor...
3.
Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance
Jalalirad M, Haddad T, Salisbury J, Radisky D, Zhang M, Schroeder M, et al.
Oncogene . 2021 Mar; 40(14):2509-2523. PMID: 33674749
Triple-negative breast cancer (TNBCs) account for 15-20% of all breast cancers and represent the most aggressive subtype of this malignancy. Early tumor relapse and progression are linked to the enrichment...
4.
NOTCH3 expression is linked to breast cancer seeding and distant metastasis
Leontovich A, Jalalirad M, Salisbury J, Mills L, Haddox C, Schroeder M, et al.
Breast Cancer Res . 2018 Sep; 20(1):105. PMID: 30180881
Background: Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. NOTCH developmental...
5.
Dominant role of the 5' TAR bulge in dimerization of HIV-1 genomic RNA, but no evidence of TAR-TAR kissing during in vivo virus assembly
Jalalirad M, Saadatmand J, Laughrea M
Biochemistry . 2012 Apr; 51(18):3744-58. PMID: 22482513
The 5' untranslated region of HIV-1 genomic RNA (gRNA) contains two stem-loop structures that appear to be equally important for gRNA dimerization: the 57-nucleotide 5' TAR, at the very 5'...
6.
RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I
Solis M, Nakhaei P, Jalalirad M, Lacoste J, Douville R, Arguello M, et al.
J Virol . 2010 Nov; 85(3):1224-36. PMID: 21084468
The rapid induction of type I interferon (IFN) is essential for establishing innate antiviral responses. During infection, cytoplasmic viral RNA is sensed by two DExD/H box RNA helicases, RIG-I and...
7.
Formation of immature and mature genomic RNA dimers in wild-type and protease-inactive HIV-1: differential roles of the Gag polyprotein, nucleocapsid proteins NCp15, NCp9, NCp7, and the dimerization initiation site
Jalalirad M, Laughrea M
Virology . 2010 Sep; 407(2):225-36. PMID: 20828778
Formation of immature genomic RNA (gRNA) dimers is exquisitely nucleocapsid (NC)-dependent in protease-inactive (PR-in) HIV-1. This establishes that Pr55gag/Pr160gag-pol has NC-dependent chaperone activity within intact HIV-1. Mutations in the proximal...