Mohammad Iqbal H Bhuiyan
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Explore the profile of Mohammad Iqbal H Bhuiyan including associated specialties, affiliations and a list of published articles.
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17
Citations
329
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Recent Articles
11.
Liu Q, Bhuiyan M, Liu R, Song S, Begum G, Young C, et al.
J Neuroinflammation
. 2021 Aug;
18(1):187.
PMID: 34454529
Background: Chronic cerebral hypoperfusion (CCH) causes white matter damage and cognitive impairment, in which astrogliosis is the major pathology. However, underlying cellular mechanisms are not well defined. Activation of Na/H...
12.
Hasan M, Luo L, Ding D, Song S, Bhuiyan M, Liu R, et al.
Theranostics
. 2021 Jan;
11(3):1295-1309.
PMID: 33391535
Immunosuppressive tumor microenvironment (TME) in glioblastoma (GBM) is one of the contributing factors for failed immunotherapies. Therefore, there is an urgent need to better understand TME and to identify novel...
13.
Song S, Huang H, Guan X, Fiesler V, Bhuiyan M, Liu R, et al.
Prog Neurobiol
. 2020 Nov;
199:101963.
PMID: 33249091
The role of astrocytes in dysregulation of blood-brain barrier (BBB) function following ischemic stroke is not well understood. Here, we investigate the effects of restoring the repair properties of astrocytes...
14.
Zhang J, Bhuiyan M, Zhang T, Karimy J, Wu Z, Fiesler V, et al.
Nat Commun
. 2020 Jan;
11(1):78.
PMID: 31911626
The SLC12A cation-Cl cotransporters (CCC), including NKCC1 and the KCCs, are important determinants of brain ionic homeostasis. SPAK kinase (STK39) is the CCC master regulator, which stimulates NKCC1 ionic influx...
15.
Huang H, Bhuiyan M, Jiang T, Song S, Shankar S, Taheri T, et al.
Stroke
. 2019 Mar;
50(4):1021-1025.
PMID: 30862257
Background and Purpose- Inhibition of brain NKCC1 (Na-K-Cl cotransporter 1) with bumetanide (BMT) is of interest in ischemic stroke therapy. However, its poor brain penetration limits the application. In this...
16.
Begum G, Song S, Wang S, Zhao H, Bhuiyan M, Li E, et al.
Glia
. 2017 Sep;
66(1):126-144.
PMID: 28925083
Stimulation of Na /H exchanger isoform 1 (NHE1) in astrocytes causes ionic dysregulation under ischemic conditions. In this study, we created a Nhe1 (Nhe1 ) mouse line with exon 5...
17.
WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats
Bhuiyan M, Song S, Yuan H, Begum G, Kofler J, Kahle K, et al.
J Cereb Blood Flow Metab
. 2016 Nov;
37(8):2780-2794.
PMID: 27798271
With-no-lysine kinase (WNK) and Na-K-2Cl cotransporter 1 (NKCC1) are involved in the pathogenesis of hypertension. In this study, we investigated the WNK-NKCC1 signaling pathway in spontaneously hypertensive rats (SHR) and...
18.
Zhang J, Gao G, Begum G, Wang J, Khanna A, Shmukler B, et al.
Sci Rep
. 2016 Oct;
6:35986.
PMID: 27782176
Cell volume homeostasis requires the dynamically regulated transport of ions across the plasmalemma. While the ensemble of ion transport proteins involved in cell volume regulation is well established, the molecular...