Mohammad H Abukhalil
Overview
Explore the profile of Mohammad H Abukhalil including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
491
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Recent Articles
1.
Al-Khawalde A, Abukhalil M, Althunibat O, Jaber F, Alaryani F, Saleh A, et al.
Tissue Cell
. 2025 Feb;
93:102767.
PMID: 39904193
Cisplatin (CIS) is effective against various cancers but causes significant side effects, including testicular damage. This study investigated the effects of taxifolin (TX), a potent flavonoid with well-known benefits, against...
2.
Abukhalil M, Al-Alami Z, Alfwuaires M, Imran M, Aladaileh S, Althunibat O
Cardiovasc Toxicol
. 2025 Jan;
25(3):455-470.
PMID: 39827225
Although 5-fluorouracil (5-FU) is widely utilized in cancer treatment, its side effects, including cardiotoxicity, limit its use. Taxifolin (TAX) is a bioactive anti-inflammatory and antioxidant flavonoid. This study aimed to...
3.
Abukhalil M, Al-Alami Z, Altaie H, Aladaileh S, Othman S, Althunibat O, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2024 Oct;
PMID: 39356319
The well-known antibiotic gentamicin (GEN) works well against a variety of pathogenic bacteria, nevertheless its therapeutic use might be limited by the possibility of nephrotoxicity. The naturally occurring flavonoid galangin...
4.
Abd El-Hack M, Kamal M, Altaie H, Youssef I, Algarni E, Almohmadi N, et al.
Toxicon
. 2023 Oct;
234:107309.
PMID: 37802220
A facultative parasite called Aspergillus flavus contaminates several important food crops before and after harvest. In addition, the pathogen that causes aspergillosis infections in humans and animals is opportunistic. Aflatoxin,...
5.
Althunibat O, Abukhalil M, Jghef M, Alfwuaires M, Algefare A, Alsuwayt B, et al.
Biomol Biomed
. 2023 Feb;
23(4):649-660.
PMID: 36762432
Taxifolin (TA) is a natural flavonoid found in many foods and medicinal plants with well-documented antioxidant and anti-inflammatory properties. Cyclophosphamide (CP) is an effective antineoplastic and immunosuppressive agent; however, it...
6.
Ebrahim A, Alfwuaires M, Abukhalil M, Alasmari F, Ahmad F, Yao R, et al.
Front Genet
. 2022 Dec;
13:1069068.
PMID: 36568394
Due to iron's essential role in cellular metabolism, most organisms must maintain their homeostasis. In this regard, the fission yeast (sp) uses two transcription factors to regulate intracellular iron levels:...
7.
Abduh M, Alruhaimi R, Alqhtani H, Hussein O, Abukhalil M, Kamel E, et al.
Life Sci
. 2022 Dec;
313:121281.
PMID: 36521549
Chlorpyrifos (CPF) is a widely used broad-spectrum pesticide with multi-organ toxic effects. Oxidative stress was found to play a role in the deleterious effects of CPF, including nephrotoxicity. This study...
8.
Obeidat H, Althunibat O, Alfwuaires M, Aladaileh S, Algefare A, Almuqati A, et al.
Biomolecules
. 2022 Nov;
12(11).
PMID: 36358896
Oxidative stress and inflammation are key components in cardiovascular diseases and heart dysfunction. Herein, we evaluated the protective effects of (+)-taxifolin (TAX), a potent flavonoid with significant antioxidant and anti-inflammatory...
9.
Al-Khawalde A, Abukhalil M, Jghef M, Alfwuaires M, Alaryani F, Aladaileh S, et al.
Int J Mol Sci
. 2022 Oct;
23(20).
PMID: 36293191
Despite its effectiveness in treating inflammatory diseases and various malignancies, methotrexate (MTX) is well known to cause hepatotoxicity, which involves increased oxidative stress and inflammation, limiting its clinical use. Herein,...
10.
Al-Amarat W, Abukhalil M, Alruhaimi R, Alqhtani H, Aldawood N, Alfwuaires M, et al.
Metabolites
. 2022 Jul;
12(7).
PMID: 35888772
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide (CP). This study investigated the protective role of the flavone apigenin (API) against CP-induced liver damage, pointing to...