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Mohammad A Amin

Explore the profile of Mohammad A Amin including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 433
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Recent Articles
1.
Cheung P, Amin M, Zhang B, Lechi F, Korsgren O, Eriksson J, et al.
Pharmaceutics . 2023 Feb; 15(2). PMID: 36839820
The progressive loss of beta-cell mass is a hallmark of diabetes and has been suggested as a complementary approach to studying the progression of diabetes in contrast to the beta-cell...
2.
Bokale-Shivale S, Amin M, Sawant R, Stevens M, Turanli L, Hallberg A, et al.
RSC Adv . 2022 Apr; 11(1):349-353. PMID: 35423044
The 3,4-dihydroquinazolinone (DHQ) moiety is a highly valued scaffold in medicinal chemistry due to the vast number of biologically-active compounds based on this core structure. Current synthetic methods to access...
3.
Cheung P, Zhang B, Puuvuori E, Estrada S, Amin M, Ye S, et al.
Biomedicines . 2021 Apr; 9(4). PMID: 33923731
A validated imaging marker for beta-cell mass would improve understanding of diabetes etiology and enable new strategies in therapy development. We previously identified the membrane-spanning protein GPR44 as highly expressed...
4.
Lu C, Amin M, Fox D
J Immunol . 2019 Dec; 204(1):3-11. PMID: 31848300
CD13/aminopeptidase N is a widely expressed ectoenzyme with multiple functions. As an enzyme, CD13 regulates activities of numerous cytokines by cleaving their N-terminals and is involved in Ag processing by...
5.
Du Y, Lu C, Morgan R, Stinson W, Campbell P, Cealey E, et al.
J Immunol . 2019 Jun; 203(2):360-369. PMID: 31189572
Aminopeptidase N/CD13 is expressed by fibroblast-like synoviocytes (FLS) and monocytes (MNs) in inflamed human synovial tissue (ST). This study examined the role of soluble CD13 (sCD13) in angiogenesis, MN migration,...
6.
Mani R, Amin M, Li X, Kalyana-Sundaram S, Veeneman B, Wang L, et al.
Cell Rep . 2016 Dec; 17(10):2620-2631. PMID: 27926866
Approximately 50% of prostate cancers are associated with gene fusions of the androgen-regulated gene TMPRSS2 to the oncogenic erythroblast transformation-specific (ETS) transcription factor ERG. The three-dimensional proximity of TMPRSS2 and...
7.
Soofi A, Wolf K, Ranghini E, Amin M, Dressler G
Am J Physiol Gastrointest Liver Physiol . 2016 Aug; 311(4):G587-G598. PMID: 27514479
Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease and is increasing with the rising rate of obesity in the developed world. Signaling pathways known to...
8.
Haak A, Tsou P, Amin M, Ruth J, Campbell P, Fox D, et al.
J Pharmacol Exp Ther . 2014 Apr; 349(3):480-6. PMID: 24706986
Systemic sclerosis (SSc), or scleroderma, similar to many fibrotic disorders, lacks effective therapies. Current trials focus on anti-inflammatory drugs or targeted approaches aimed at one of the many receptor mechanisms...
9.
Isozaki T, Amin M, Ruth J, Campbell P, Tsou P, Ha C, et al.
Arthritis Rheumatol . 2014 Apr; 66(8):2047-58. PMID: 24692243
Objective: To determine the role of α(1,2)-linked fucosylation of proteins by fucosyltransferase 1 (FUT1) in rheumatoid arthritis (RA) angiogenesis. Methods: Analysis of α(1,2)-linked fucosylated proteins in synovial tissue (ST) samples...
10.
Amin M, Campbell P, Ruth J, Isozaki T, Rabquer B, Alex Stinson W, et al.
Ann Rheum Dis . 2014 Mar; 74(7):1459-66. PMID: 24665114
Objectives: Angiogenesis contributes to the pathogenesis of rheumatoid arthritis. Fucosyltransferases (Futs) are involved in angiogenesis and tumour growth. Here, we examined the role of Fut1 in angiogenesis and K/BxN serum...