Mohamed El Ayeb
Overview
Explore the profile of Mohamed El Ayeb including associated specialties, affiliations and a list of published articles.
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Articles
66
Citations
770
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Recent Articles
1.
Limam I, Abdelkarim M, El Ayeb M, Crepin M, Marrakchi N, Di Benedetto M
Int J Mol Sci
. 2023 Aug;
24(15).
PMID: 37569595
Venoms are a rich source of bioactive compounds, and among them is leberagin-C (Leb-C), a disintegrin-like protein derived from the venom of snakes. Leb-C has shown promising inhibitory effects on...
2.
Ben Abderrazek R, Ksouri A, Idoudi F, Dhaouadi S, Hamdi E, Vincke C, et al.
Front Immunol
. 2022 May;
13:863012.
PMID: 35514999
Scorpion envenoming is a severe health problem in many regions causing significant clinical toxic effects and fatalities. In the Middle East/North Africa (MENA) region, scorpion stings are responsible for devastating...
3.
Tabka H, Cheikh A, Maatoug S, El Ayeb M, Bendahhou S, Benkhalifa R
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33003279
Kv3.1 channel is abundantly expressed in neurons and its dysfunction causes sleep loss, neurodegenerative diseases and depression. Fluoxetine, a serotonin selective reuptake inhibitor commonly used to treat depression, acts also...
4.
Morjen M, Othman H, AbdelKafi-Koubaa Z, Messadi E, Jebali J, El Ayeb M, et al.
Int J Biol Macromol
. 2018 Jun;
117:790-799.
PMID: 29870815
Through the recent development of knowledge in biotechnology and bioinformatics, snake venoms are widely used to develop new drugs to treat diseases such as hypertension and cancer. We have previously...
5.
Bezine M, Maatoug S, Khalifa R, Debbabi M, Zarrouk A, Wang Y, et al.
Biochimie
. 2018 Feb;
153:56-69.
PMID: 29462682
Little is known about K regulation playing major roles in the propagation of nerve impulses, as well as in apoptosis and inflammasome activation involved in neurodegeneration. As increased levels of...
6.
Bensaoud C, AbdelKafi-Koubaa Z, Mabrouk H, Morjen M, Hmila I, Rhim A, et al.
J Med Entomol
. 2017 Oct;
54(6):1476-1482.
PMID: 29029126
Hard ticks (Acari: Ixodidae) are blood-sucking ectoparasites characterized by the extended period of their attachment to their host. To access their bloodmeal, ticks secrete saliva containing a range of molecules...
7.
Zarrouk A, Debbabi M, Bezine M, Karym E, Badreddine A, Rouaud O, et al.
Curr Alzheimer Res
. 2017 May;
15(4):303-312.
PMID: 28474568
Background: There are now significant evidences that lipid metabolism is affected in numerous neurodegenerative diseases including Alzheimer's disease. These dysfunctions lead to abnormal levels of certain lipids in the brain,...
8.
Jridi I, Catacchio I, Majdoub H, Shahbazzadeh D, El Ayeb M, Frassanito M, et al.
Toxicon
. 2016 Dec;
126:38-46.
PMID: 27940138
In a previous study, we reported the identification of Hemilipin, the first secreted heterodimeric phospholipase A2 (sPLA2) from Hemiscorpius lepturus scorpion venom and demonstrated its effective inhibition of all angiogenesis...
9.
Hassiki R, Labro A, Benlasfar Z, Vincke C, Somia M, El Ayeb M, et al.
Int J Biol Macromol
. 2016 Jun;
93(Pt A):167-171.
PMID: 27320844
Voltage-gated potassium (Kv) channels form cells repolarizing power and are commonly expressed in excitable cells. In non-excitable cells, Kv channels such as Kv2.1 are involved in cell differentiation and growth....
10.
Bairam D, Aissa I, Louati H, Othman H, AbdelKafi-Koubaa Z, Krayem N, et al.
Int J Biol Macromol
. 2016 May;
89:640-6.
PMID: 27164498
The present study investigated the kinetic and interfacial properties of two secreted phospholipases isolated from Tunisian vipers'venoms: Cerastes cerastes (CC-PLA2) and Macrovipera lebetina transmediterranea (MVL-PLA2). Results show that these enzymes...