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Mohamed A Abdel-Rahman

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Citations 426
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Recent Articles
11.
Deng Z, Gao Y, Nguyen T, Chai J, Wu J, Li J, et al.
Toxins (Basel) . 2023 May; 15(5). PMID: 37235381
Research has been conducted to investigate the potential application of scorpion venom-derived peptides in cancer therapy. Smp43, a cationic antimicrobial peptide from venom, has been found to exhibit suppressive activity...
12.
Abdel-Rahman M, Shibl M, Mahmoud M
Sci Rep . 2023 Apr; 13(1):6248. PMID: 37069216
This work reports a thermo-kinetic study on unimolecular thermal decomposition of some ethoxyquinolines and ethoxyisoquinolines derivatives (1-ethoxyisoquinoline (1-EisoQ), 2-ethoxyquinoline (2-EQ), 3-ethoxyquinoline (3-EQ), 3-ethoxyisoquinoline (3-EisoQ), 4-ethoxyquinoline (4-EQ), 4-ethoxyisoquinoline (4-EisoQ), 5-ethoxyquinoline (5-EQ),...
13.
Shojaei S, Shiroudi A, Abdel-Rahman M
Heliyon . 2022 Nov; 8(11):e11274. PMID: 36339763
The gas-phase decomposition kinetics of isopropyl acetate (IPA) and its methyl, bromide and hydroxyl derivatives into the corresponding acid and propene were investigated using density functional theory (DFT) with the...
14.
Nguyen T, Guo R, Chai J, Wu J, Liu J, Chen X, et al.
Toxins (Basel) . 2022 Oct; 14(10). PMID: 36287985
Scorpion-venom-derived peptides have become a promising anticancer agent due to their cytotoxicity against tumor cells via multiple mechanisms. The suppressive effect of the cationic antimicrobial peptide Smp24, which is derived...
15.
Guo R, Chen X, Nguyen T, Chai J, Gao Y, Wu J, et al.
Toxins (Basel) . 2022 Sep; 14(9). PMID: 36136528
Non-small cell lung cancer (NSCLC) is the leading cause of death in lung cancer due to its aggressiveness and rapid migration. The potent antitumor effect of Smp24, an antimicrobial peptide...
16.
Magdy N, Nafie M, El-Naggar M, Abu El-Regal M, Abdel Azeiz A, Abdel-Rahman M, et al.
J Biomol Struct Dyn . 2022 Sep; 41(16):7786-7793. PMID: 36129119
Cancer is still an area of continuous research for finding more effective and selective agents, so our study aimed to explore new anticancer medicines from Cone snails' venoms as marine...
17.
Guo R, Liu J, Chai J, Gao Y, Abdel-Rahman M, Xu X
Toxins (Basel) . 2022 Jul; 14(7). PMID: 35878176
Smp24, a cationic antimicrobial peptide identified from the venom gland of the Egyptian scorpion , shows variable cytotoxicity on various tumor (KG1a, CCRF-CEM and HepG2) and non-tumor (CD34, HRECs, HACAT)...
18.
El-Meligy A, El-Demerdash S, Abdel-Rahman M, Mahmoud M, Taketsugu T, El-Nahas A
ACS Omega . 2022 May; 7(16):14222-14238. PMID: 35559155
Tautomerization of 2-(2-hydroxyphenyl)-1-azaazulene () in the gas phase and ethanol has been studied using B3LYP, M06-2X, and ωB97XD density functional theory (DFT) with different basis sets. For more accurate data,...
19.
Elrayess R, Mohallal M, Mobarak Y, Ebaid H, Haywood-Small S, Miller K, et al.
Front Pharmacol . 2022 Jan; 12:788874. PMID: 35082671
Within the last decade, several peptides have been identified according to their ability to inhibit the growth of microbial pathogens. These antimicrobial peptides (AMPs) are a part of the innate...
20.
Chai J, Yang W, Gao Y, Guo R, Peng Q, Abdel-Rahman M, et al.
J Nat Prod . 2021 Dec; 84(12):3147-3160. PMID: 34866381
Smp43, a cationic antimicrobial peptide identified from the venom gland of the Egyptian scorpion , shows cytotoxicity toward hepatoma cell line HepG2 by membrane disruption. However, its underlying detailed mechanisms...