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Mohamed-Elamir F Hegazy

Explore the profile of Mohamed-Elamir F Hegazy including associated specialties, affiliations and a list of published articles. Areas
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Articles 106
Citations 1112
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Recent Articles
1.
Abdeljawaad K, Abdelrahman A, Sidhom P, Tallima H, Shoeib T, Mekhemer G, et al.
J Mol Graph Model . 2025 Mar; 137:108997. PMID: 40043638
P-glycoprotein (P-gp) transporter is included in the failure of various carcinoma chemotherapeutics because of the multidrug resistance (MDR) phenomenon, in which the chemotherapeutic drugs are eliminated from target cells. Consequently,...
2.
Saleh I, Elsayed W, Hussien T, Elshamy A, Mohamed T, Hegazy M
Nat Prod Res . 2024 Dec; :1-7. PMID: 39679927
A new cadinane-type sesquiterpene glucoside, 10-hydroxy, 1(H), 6(H), 7(H), 8(H)-cadinane-4-en-8-O--D-glucoside () as well as, 2 known analogues [sinaicin ()- linichlorinA ()], were isolated from the CHCl:MeOH organic extract of ....
3.
Ibrahim M, Mahmoud D, Abdelrahman A, Abdeljawaad K, Mekhemer G, Shoeib T, et al.
PLoS One . 2024 Nov; 19(11):e0314422. PMID: 39585898
Mycobacterium tuberculosis is a lethal human pathogen, with the key flavoenzyme for catalyzing bacterial cell-wall biosynthesis, decaprenylphosphoryl-D-ribose oxidase (DprE1), considered an Achilles heal for tuberculosis (TB) progression. Inhibition of DprE1...
4.
Nabih H, Yucer R, Mahmoud N, Dawood M, Elbadawi M, Shahhamzehei N, et al.
Phytomedicine . 2024 Oct; 135:156023. PMID: 39368339
Background: Leukemia is one of the most lethal cancers worldwide and represents the sixth-leading cause of cancer deaths. The results of leukemia treatment have not been as positive as desired,...
5.
Ibrahim M, Ali S, Abdelrahman A, Abdeljawaad K, Sidhom P, Sayed S, et al.
Chem Biodivers . 2024 Jul; 21(11):e202401238. PMID: 39075025
The evolutionarily conserved extracellular signal-regulated kinase 2 (ERK2) is involved in regulating cellular signaling in both normal and pathological conditions. ERK2 expression is critical for human development, while hyperactivation is...
6.
Zou Q, Chunduru J, LaRoe N, Yang Y, Mohamed T, M Hegazi N, et al.
Fitoterapia . 2024 Jul; 177:106124. PMID: 38996879
The Solanaceae family and the Withania genus specifically are rich sources of medicinal plants. Liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS/MS) revealed a predominance of withanolides from an organic...
7.
Hamed A, Nabih H, El-Rashedy A, Mohamed T, Mostafa O, K Ali S, et al.
3 Biotech . 2024 May; 14(5):144. PMID: 38706927
Sustained inflammatory responses can badly affect several vital organs and lead to chronic inflammation-related disorders, such as atherosclerosis, pneumonia, rheumatoid arthritis, obesity, diabetes, Alzheimer's disease, and cancers. is one of...
8.
M Hegazi N, Mohamed T, Salama A, Hamed A, Saad H, Saleh I, et al.
Food Funct . 2024 Mar; 15(8):4354-4364. PMID: 38533683
Alzheimer's Disease (AD) is a fatal age-related neurodegenerative condition with a multifactorial etiology contributing to 70% of dementia globally. The search for a multi-target agent to hit different targets involved...
9.
Abd El-Razek M, El-Desoky A, Elgahamy A, Bata S, Mohamed T, Hegazy M
Nat Prod Res . 2024 Feb; :1-11. PMID: 38353145
Phytochemical characterisation of the polar fraction of extract led to the isolation of glycerylerigeroside (), a unique γ-pyrone derivative. Structure of was decided by intensive study of NMR and mass...
10.
Abd El-Razek M, Eissa I, Al-Karmalawy A, Elrashedy A, El-Desoky A, Aboelmagd M, et al.
J Biomol Struct Dyn . 2024 Jan; :1-13. PMID: 38265952
Five known furofuran lignans, -sesamin (), 5-methoxysesamin (), -magnolin (), kobusin () and yangambin () were isolated for the first-time from the oleo-gum resin of . This is the first...