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Mohamad Azhar

Explore the profile of Mohamad Azhar including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 1477
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Recent Articles
1.
Chakrabarti M, Chattha A, Nair A, Jiao K, Potts J, Wang L, et al.
J Cardiovasc Dev Dis . 2023 Dec; 10(12). PMID: 38132651
The transforming growth factor beta (TGFβ) and Hippo signaling pathways are evolutionarily conserved pathways that play a critical role in cardiac fibroblasts during embryonic development, tissue repair, and fibrosis. TGFβ...
2.
Viola M, Chavero-Pieres M, Modave E, Delfini M, Stakenborg N, Cuende Estevez M, et al.
Nature . 2023 Jun; 618(7966):818-826. PMID: 37316669
Correct development and maturation of the enteric nervous system (ENS) is critical for survival. At birth, the ENS is immature and requires considerable refinement to exert its functions in adulthood....
3.
Chakrabarti M, Bhattacharya A, Gebere M, Johnson J, Ayub Z, Chatzistamou I, et al.
Front Cardiovasc Med . 2022 Aug; 9:770065. PMID: 35928937
Aims: Calcific aortic valve disease (CAVD) is a progressive heart disease that is particularly prevalent in elderly patients. The current treatment of CAVD is surgical valve replacement, but this is...
4.
Nobre A, Risson E, Singh D, Di Martino J, Cheung J, Wang J, et al.
Nat Cancer . 2022 Jan; 2(3):327-339. PMID: 34993493
In the bone marrow (BM) microenvironment, where breast cancer (BC) disseminated tumour cells (DTCs) can remain dormant for decades, NG2/Nestin mesenchymal stem cells (MSCs) promote hematopoietic stem cell quiescence. Here,...
5.
Lane B, Chakrabarti M, Ferruzzi J, Azhar M, Eberth J
J Biomech . 2021 Jun; 125:110543. PMID: 34174532
Transforming growth factor-beta (TGFβ-1, -2, -3) ligands act through a common receptor complex yet each is expressed in a unique and overlapping fashion throughout development. TGFβ plays a role in...
6.
Carver W, Fix E, Fix C, Fan D, Chakrabarti M, Azhar M
J Cell Physiol . 2021 May; 236(11):7440-7449. PMID: 34041746
Cardiac fibrosis accompanies a number of pathological conditions and results in altered myocardial structure, biomechanical properties and function. The signaling networks leading to fibrosis are complex, contributing to the general...
7.
Bhattacharya A, Al-Sammarraie N, Gebere M, Johnson J, Eberth J, Azhar M
J Cardiovasc Dev Dis . 2021 Apr; 8(3). PMID: 33801433
Among the three transforming growth factor beta (TGFβ) ligands, TGFβ2 is essential for heart development and is produced by multiple cell types, including myocardium. Heterozygous mutations in in patients of...
8.
Wu W, Wang C, Zang H, Qi L, Azhar M, Nagarkatti M, et al.
Arterioscler Thromb Vasc Biol . 2020 Jun; 40(8):1870-1890. PMID: 32493169
Objective: Neointima formation is a primary cause of intermediate to late vein graft (VG) failure. However, the precise source of neointima cells in VGs remains unclear. Approach and Results: Herein...
9.
Chakrabarti M, Al-Sammarraie N, Gebere M, Bhattacharya A, Chopra S, Johnson J, et al.
J Cardiovasc Dev Dis . 2020 May; 7(2). PMID: 32456345
Transforming growth factor beta3 () gene mutations in patients of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD1) and Loeys-Dietz syndrome-5 (LDS5)/Rienhoff syndrome are associated with cardiomyopathy, cardiac arrhythmia, cardiac fibrosis, cleft palate,...
10.
Takahashi H, Alves C, Stanford K, Middelbeek R, Nigro P, Ryan R, et al.
Nat Metab . 2019 Apr; 1(2):291-303. PMID: 31032475
Exercise improves health and well-being across diverse organ systems, and elucidating mechanisms underlying the beneficial effects of exercise can lead to new therapies. Here, we show that transforming growth factor-β2...