Mobarak Abu Mraheil
Overview
Explore the profile of Mobarak Abu Mraheil including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
691
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Recent Articles
1.
El Aila N, Al Laham N, Doijad S, Imirzalioglu C, Mraheil M
BMC Microbiol
. 2024 Oct;
24(1):393.
PMID: 39379824
Background: The worldwide prevalence of multi-drug resistance (MDR) in Gram-negative bacteria (GNB), particularly related to extended-spectrum beta-lactamases (ESBLs) and carbapenemases, poses significant global public health and clinical challenges. Objectives: To...
2.
Bazant J, Weiss A, Baldauf J, Schermuly R, Hain T, Lucas R, et al.
Front Immunol
. 2024 Jun;
15:1414195.
PMID: 38903521
Introduction: Protein kinases are indispensable reversible molecular switches that adapt and control protein functions during cellular processes requiring rapid responses to internal and external events. Bacterial infections can affect kinase-mediated...
3.
Bazant J, Ott B, Hudel M, Hain T, Lucas R, Mraheil M
Toxins (Basel)
. 2023 Oct;
15(10).
PMID: 37888624
is the leading cause of community-acquired pneumonia. The pore-forming cholesterol-dependent cytolysin (CDC) pneumolysin (PLY) and the physiological metabolite hydrogen peroxide (HO) can greatly increase the virulence of pneumococci. Although most...
4.
Klabunde B, Wesener A, Bertrams W, Beinborn I, Paczia N, Surmann K, et al.
Nat Commun
. 2023 Oct;
14(1):5818.
PMID: 37783679
Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic,...
5.
Frantz R, Gwozdzinski K, Gisch N, Doijad S, Hudel M, Wille M, et al.
Microbiol Spectr
. 2023 Apr;
11(3):e0359222.
PMID: 37071007
The envelope stress response (ESR) of Gram-negative enteric bacteria senses fluctuations in nutrient availability and environmental changes to avert damage and promote survival. It has a protective role toward antimicrobials,...
6.
Baiomy A, Serry F, Kadry A, Yahya G, Doijad S, Mostafa A, et al.
Pathogens
. 2023 Mar;
12(3).
PMID: 36986348
The appearance of persister cells with low metabolic rates are key factors leading to antibiotic treatment failure. Such persisters are multidrug tolerant and play a key role in the recalcitrance...
7.
Hemdan B, Mostafa A, Elbatanony M, El-Feky A, Paunova-Krasteva T, Stoitsova S, et al.
PLoS One
. 2023 Mar;
18(3):e0282729.
PMID: 36888689
The leaves of Azadirachta indica L. and Melia azedarach L., belonging to Meliaceae family, have been shown to have medicinal benefits and are extensively employed in traditional folk medicine. Herein,...
8.
Teubner L, Frantz R, La Pietra L, Hudel M, Bazant J, Lochnit G, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499346
Protein secretion plays a central role in modulating interactions of the human pathogen with its environment. Recently, secretion of RNA has emerged as an important strategy used by the pathogen...
9.
Hegazy A, Mostafa I, Elshaier Y, Mahmoud S, Abo Shama N, Shehata M, et al.
ACS Omega
. 2022 Nov;
7(45):41212-41223.
PMID: 36406485
The evolution of drug-resistant viral strains following natural acquisition of resistance mutations is a major obstacle to antiviral therapy. Besides the improper prescription of the currently licensed anti-influenza medications, M2-blockers...
10.
Banovic F, Schulze S, Mraheil M, Hain T, Chakraborty T, Orian-Rousseau V, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361697
The human central nervous system (CNS) is separated from the blood by distinct cellular barriers, including the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CFS) barrier (BCSFB). Whereas at the...