Miyoko Hirose
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Explore the profile of Miyoko Hirose including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
393
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Recent Articles
1.
Wang X, Watanabe S, Oide H, Hirose M, Itatsu T, Osada T, et al.
J Gastroenterol Hepatol
. 2017 Oct;
13(S1):S14-S18.
PMID: 28976684
Prostaglandin E (PGE ) has been reported to have, experimentally and clinically, a protective effect against liver damage. This effect may result from the relaxation of hepatic stellate cells, whose...
2.
Enomoto N, Takei Y, Hirose M, Yamashina S, Ikejima K, Kitamura T, et al.
Alcohol Clin Exp Res
. 2004 Aug;
28(8 Suppl Proceedings):145S-147S.
PMID: 15318102
Background: Sensitivity of Kupffer cells to endotoxin [lipopolysaccharide (LPS)] and overproduction of tumor necrosis factor-alpha (TNF-alpha) are critical for progression of alcoholic liver injury. Therefore, suppression of TNF-alpha should prove...
3.
Thalidomide Prevents Alcoholic Liver Injury in Rats Through Inhibition of Kupffer Cell Sensitization
Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, Sato N
Comp Hepatol
. 2004 Feb;
3 Suppl 1:S37.
PMID: 14960189
No abstract available.
4.
Ikejima K, Lang T, Zhang Y, Yamashina S, Honda H, Yoshikawa M, et al.
Comp Hepatol
. 2004 Feb;
3 Suppl 1:S12.
PMID: 14960164
Emerging evidence has suggested a critical role of leptin in hepatic inflammation and fibrogenesis, however, the precise mechanisms underlying the profibrogenic action of leptin in the liver has not been...
5.
Tsukada S, Enomoto N, Takei Y, Hirose M, Ikejima K, Kitamura T, et al.
Alcohol Clin Exp Res
. 2003 Sep;
27(8 Suppl):7S-11S.
PMID: 12960499
Background: Sensitization of Kupffer cells (KC) to lipopolysaccharide (LPS) and overproduction of tumor necrosis factor (TNF)-alpha play important roles in the pathogenesis of alcoholic liver damage and sepsis-associated organ injury....
6.
Enomoto N, Takei Y, Hirose M, Kitamura T, Ikejima K, Sato N
Alcohol Clin Exp Res
. 2003 Sep;
27(8 Suppl):2S-6S.
PMID: 12960498
Background: Activation of Kupffer cells by lipopolysaccharide (LPS) plays a pivotal role in the onset of pathophysiological events that occur during endotoxemia, and intracellular calcium concentration ([Ca2+]i) is involved in...
7.
Tsune I, Ikejima K, Hirose M, Yoshikawa M, Enomoto N, Takei Y, et al.
Gastroenterology
. 2003 Sep;
125(3):775-85.
PMID: 12949723
Background & Aims: In this study, the effect of dietary glycine on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid (TNBS) and dextran sulfate sodium (DSS) in the rat was evaluated....
8.
Enomoto N, Takei Y, Hirose M, Konno A, Shibuya T, Matsuyama S, et al.
J Pharmacol Exp Ther
. 2003 Jun;
306(3):846-54.
PMID: 12805475
Agonists of peroxisome proliferator-activated receptor (PPAR)-gamma have been shown to reduce tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance. On the other hand, sensitization of Kupffer cells to lipopolysaccharide (LPS) and their...
9.
Shibuya T, Takei Y, Hirose M, Ikejima K, Enomoto N, Maruyama A, et al.
Biochem Biophys Res Commun
. 2002 Oct;
298(1):10-16.
PMID: 12379212
Altered gene expression of liver sinusoidal endothelial cells (SECs) is associated with impaired immune response. Here we report that the decoy technique effectively suppresses TNFalpha-induced ICAM-1 expression in SEC. An...
10.
Konno A, Enomoto N, Takei Y, Hirose M, Ikejima K, Sato N
Alcohol Clin Exp Res
. 2002 Aug;
26(8 Suppl):70S-74S.
PMID: 12198379
Background: Oral contraceptives are widely used; however, these drugs occasionally cause liver injury. Recently, it was reported that estriol worsens alcoholic liver injury by the mechanism involving activation of Kupffer...