Mitsuhiro Shimizu
Overview
Explore the profile of Mitsuhiro Shimizu including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
137
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Recent Articles
1.
Shimizu M, Fujie T, Shibata M, Komori T, Ninomiya K, Takahashi K, et al.
Chem Commun (Camb)
. 2025 Feb;
PMID: 40017265
Zwitterionic liquids have attracted significant attention in various fields due to their low-toxicity and the ability to tune their functional properties. However, despite being liquid in thermo-dynamic definition, zwitterionic liquids...
2.
Kawakami K, Maeda S, Tanimoto Y, Shimizu M, Kato H
Genes Genet Syst
. 2024 Mar;
99.
PMID: 38447993
The budding yeast Saccharomyces cerevisiae is an excellent model organism for studying chromatin regulation with high-resolution genome-wide analyses. Since newly generated genome-wide data are often compared with publicly available datasets,...
3.
Kato H, Shimizu M, Urano T
BMC Bioinformatics
. 2021 Jun;
22(1):322.
PMID: 34120589
Background: Assessing the nucleosome-forming potential of specific DNA sequences is important for understanding complex chromatin organization. Methods for predicting nucleosome positioning include bioinformatics and biophysical approaches. An advantage of bioinformatics...
4.
Katsumata K, Ichikawa Y, Fuse T, Kurumizaka H, Yanagida A, Urano T, et al.
Biochem Biophys Res Commun
. 2021 Apr;
556:179-184.
PMID: 33839413
Trinucleotide repeat sequences (TRSs), consisting of 10 unique classes of repeats in DNA, are members of microsatellites and abundantly and non-randomly distributed in many eukaryotic genomes. The lengths of TRSs...
5.
Fuse T, Yanagida A, Shimizu M
Biol Pharm Bull
. 2018 Dec;
42(2):289-294.
PMID: 30531092
In eukaryotic genomes, the nucleosome is the structural and functional unit, and its position and dynamics are important for gene expression control and epigenetic regulation. Epigenetics is an important mechanism...
6.
Fuse T, Katsumata K, Morohoshi K, Mukai Y, Ichikawa Y, Kurumizaka H, et al.
PLoS One
. 2017 Oct;
12(10):e0186974.
PMID: 29073207
Micrococcal nuclease (MNase) has been widely used for analyses of nucleosome locations in many organisms. However, due to its sequence preference, the interpretations of the positions and occupancies of nucleosomes...
7.
Ichikawa Y, Morohashi N, Tomita N, Mitchell A, Kurumizaka H, Shimizu M
Biochem Biophys Res Commun
. 2016 May;
476(2):57-62.
PMID: 27208777
Nucleosome-depleted regions (NDRs) (also called nucleosome-free regions or NFRs) are often found in the promoter regions of many yeast genes, and are formed by multiple mechanisms, including the binding of...
8.
Ichikawa Y, Nishimura Y, Kurumizaka H, Shimizu M
Biomol Concepts
. 2015 Feb;
6(1):67-75.
PMID: 25720088
Telomeres are DNA-protein complexes located at the ends of linear eukaryotic chromosomes, and are essential for chromosome stability and maintenance. In most organisms, telomeres consist of tandemly repeated sequences of...
9.
Ichikawa Y, Morohashi N, Nishimura Y, Kurumizaka H, Shimizu M
Nucleic Acids Res
. 2013 Nov;
42(3):1541-52.
PMID: 24174540
Telomeric DNAs consist of tandem repeats of G-clusters such as TTAGGG and TG1-3, which are the human and yeast repeat sequences, respectively. In the yeast Saccharomyces cerevisiae, the telomeric repeats...
10.
Miki K, Shimizu M, Fujii M, Takayama S, Hossain M, Ayusawa D
FEBS J
. 2010 Nov;
277(21):4539-48.
PMID: 21040474
5-Bromodeoxyuridine (BrdU) modulates the expression of particular genes associated with cellular differentiation and senescence when incorporated into DNA instead of thymidine (dThd). To date, a molecular mechanism for this phenomenon...