Mitsuaki Takeuchi
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Explore the profile of Mitsuaki Takeuchi including associated specialties, affiliations and a list of published articles.
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10
Citations
56
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Recent Articles
1.
Nakamura T, Tanimoto H, Okamoto M, Takeuchi M, Tsubamoto Y, Noda H
Diabetes Metab Syndr Obes
. 2021 Mar;
14:1095-1105.
PMID: 33727843
Introduction: Glucose-dependent insulinotropic polypeptide (GIP) plays a crucial role in the regulation of lipid metabolism via lipoprotein lipase (LPL). GIP receptor antagonist, SKL-14959, suppressed the weight gain in the diet-induced...
2.
Takeuchi M, Okamoto M, Tamura M, Murase T, Watanabe N
Drug Res (Stuttg)
. 2019 May;
69(9):479-486.
PMID: 31083740
Background: Long-acting glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used for treatment of type 2 diabetes (T2DM) in the United States, the European Union, and Japan. In our previous...
3.
Takeuchi M, Okamoto M, Okamoto R, Kinoshita H, Yamaguchi Y, Watanabe N
Peptides
. 2018 Feb;
102:8-15.
PMID: 29391187
In the course of our search for new GLP-1 analogs, we screened a number of [Ser]-GLP-1 analogs using the C-terminal helix 3 of the albumin binding domain 3 of protein...
4.
Fujita A, Matsumoto Y, Takeuchi M, Ryuto H, Takaoka G
Phys Chem Chem Phys
. 2016 Jan;
18(7):5464-70.
PMID: 26821883
Physical vapor evaporation of metals on low vapor pressure liquids is a simple and clean method to synthesize nanoparticles and thin films, though only little work has been conducted so...
5.
Takeuchi M, Hayashi K, Imanaka K, Ryuto H, Takaoka G
Rev Sci Instrum
. 2014 Mar;
85(2):02A502.
PMID: 24593425
Electron-ionization-type polyatomic molecular ion source with low fragment was developed by using a pair of ring-shaped Sm-Co magnets. The magnets were placed forward and backward side of ionization part to...
6.
Kato N, Oka M, Murase T, Yoshida M, Sakairi M, Yakufu M, et al.
Org Med Chem Lett
. 2012 Mar;
1(1):7.
PMID: 22373386
Focused structure-activity relationships of isoindoline class DPP-IV inhibitors have led to the discovery of 4b as a highly selective, potent inhibitor of DPP-IV. In vivo studies in Wistar/ST rats showed...
7.
Kubo A, Stull R, Takeuchi M, Bonham K, Gouon-Evans V, Sho M, et al.
PLoS One
. 2011 Sep;
6(9):e24058.
PMID: 21931641
In order to define the molecular mechanisms regulating the specification and differentiation of pancreatic β-islet cells, we investigated the effect of upregulating Pdx1 and Ngn3 during the differentiation of the...
8.
The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm
Kubo A, Kim Y, Irion S, Kasuda S, Takeuchi M, Ohashi K, et al.
Hepatology
. 2010 Jan;
51(2):633-41.
PMID: 20063280
We investigated the role of the hematopoietically expressed homeobox (Hex) in the differentiation and development of hepatocytes within embryonic stem cell (ESC)-derived embryoid bodies (EBs). Analyses of hepatic endoderm derived...
9.
Takeuchi M, Gotoh Y, Tsuji H, Ishikawa J, Sakai S
Rev Sci Instrum
. 2008 Mar;
79(2 Pt 2):02B712.
PMID: 18315203
A low energy ion beam system for space charge compensation (SCC) experiments was developed and evaluated. This system was designed for observation of SCC of a positive ion beam with...
10.
Iwasaki M, Yoshimura Y, Asahi S, Saito K, Sakai S, Morita S, et al.
Drug Metab Pharmacokinet
. 2005 Feb;
19(6):444-52.
PMID: 15681899
As a part of the studies conducted by the Pharma SNPs Consortium (PSC), the enzyme activities of CYP1A2, CYP2A6 and CYP2B6 variants with altered amino acids as a result of...