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Misba Beerahee

Explore the profile of Misba Beerahee including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 176
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Recent Articles
1.
Llanos-Paez C, Ambery C, Yang S, Beerahee M, Plan E, Karlsson M
J Pharmacokinet Pharmacodyn . 2023 Mar; 50(4):297-314. PMID: 36947282
Model-based meta-analysis (MBMA) is an approach that integrates relevant summary level data from heterogeneously designed randomized controlled trials (RCTs). This study not only evaluated the predictability of a published MBMA...
2.
Begg M, Amour A, Jarvis E, Tang T, Franco S, Want A, et al.
Pulm Pharmacol Ther . 2023 Feb; 79:102201. PMID: 36841351
Activated PI3Kδ Syndrome (APDS) is a rare inherited inborn error of immunity caused by mutations that constitutively activate the p110 delta isoform of phosphoinositide 3-kinase (PI3Kδ), resulting in recurring pulmonary...
3.
Okour M, Thapar M, Farrell C, Lukas M, Beghetti M, Beerahee M
J Clin Pharmacol . 2022 Dec; 63(5):593-603. PMID: 36579617
This study aimed to develop a population pharmacokinetic (PK) model of ambrisentan in pediatric patients (8 to <18 years) with pulmonary arterial hypertension (PAH) and compare pediatric ambrisentan systemic exposure...
4.
Mohan D, Rossiter H, Watz H, Fogarty C, Evans R, Man W, et al.
Thorax . 2022 Oct; 78(3):258-266. PMID: 36283827
Background: Selective androgen receptor modulators (SARMs) increase muscle mass via the androgen receptor. This phase 2A trial investigated the effects of a SARM, GSK2881078, in conjunction with exercise, on leg...
5.
Yang S, Simeoni M, Beerahee M
Clin Pharmacol Ther . 2022 Mar; 111(6):1286-1295. PMID: 35271735
Asthma is a chronic disease of the lungs characterized by airway inflammation, bronchoconstriction, and increased airway responsiveness. Forced expiratory volume in the first second (FEV1) is used as a measure...
6.
Llanos-Paez C, Ambery C, Yang S, Beerahee M, Plan E, Karlsson M
Pharm Res . 2022 Mar; 39(8):1779-1787. PMID: 35233731
Purpose: The current study aimed to illustrate how a non-linear mixed effect (NLME) model-based analysis may improve confidence in a Phase III trial through more precise estimates of the drug...
7.
Ludbrook V, Hanrott K, Kreindler J, Marks-Konczalik J, Bird N, Hewens D, et al.
ERJ Open Res . 2021 Aug; 7(3). PMID: 34350286
Objective: Airway sensory nerves involved in the cough reflex are activated by adenosine triphosphate (ATP) agonism of P2X purinoceptor 3 (P2X3) receptors. Transient receptor potential vanilloid 4 (TRPV4) channel activation...
8.
Llanos-Paez C, Ambery C, Yang S, Tabberer M, Beerahee M, Plan E, et al.
AAPS J . 2021 Jun; 23(4):79. PMID: 34080077
This study aimed to illustrate how a new methodology to assess clinical trial outcome measures using a longitudinal item response theory-based model (IRM) could serve as an alternative to mixed...
9.
Mole S, Harry A, Fowler A, Hotee S, Warburton J, Waite S, et al.
Pulm Pharmacol Ther . 2020 Nov; 64:101977. PMID: 33189900
Background: Acute Respiratory Distress Syndrome (ARDS) is associated with increased pulmonary-vascular permeability. In the lung, transient receptor potential vanilloid 4 (TRPV4), a Ca-permeable cation channel, is a regulator of endothelial...
10.
Largajolli A, Beerahee M, Yang S
J Pharmacokinet Pharmacodyn . 2019 Nov; 46(6):627. PMID: 31728746
The article [Bayesian approach to investigate a two-state mixed model of COPD exacerbations], written by [Anna Largajolli, Misba Beerahee, Shuying Yang], was originally published electronically on the publisher's internet portal...