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Mirthe H Schoots

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Citations 770
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Recent Articles
1.
Holstein H, Bouwknegt D, Visschedijk M, Bulthuis M, Reinders-Luinge M, Schoots M, et al.
Free Radic Biol Med . 2025 Mar; PMID: 40089080
Background: Inflammatory bowel disease (IBD) often presents during the fertile age and may affect pregnancy outcomes. Both IBD and selected pregnancy complications involve oxidative stress. Soluble FMS-like tyrosine kinase-1 (sFlt-1)...
2.
Abrudan A, Schoots M, Kooi E, Gordijn S, Kraft K, Prins J, et al.
Pediatr Res . 2025 Feb; PMID: 39934646
Background: Preterm infants are at risk for neurodevelopmental disabilities later in life, like motor delays and cerebral palsy (CP). The placenta plays a critical role throughout pregnancy, particularly in preterm...
3.
Feenstra M, Schoots M, Bezemer R, van der Meeren L, Nikkels P, Goor H, et al.
Placenta . 2024 Dec; 159():39-46. PMID: 39616670
Objectives: Placental pathology lesions are common in early-onset fetal growth restriction (eoFGR). Therapeutic interventions to improve eoFGR outcomes are needed. In the international STRIDER trials (Sildenafil Therapy In Dismal prognosis...
4.
Feenstra M, Bourgonje M, Bourgonje A, Schoots M, Hillebrands J, Muller Kobold A, et al.
Antioxidants (Basel) . 2024 Jan; 13(1). PMID: 38247471
Background: Placental insufficiency is an important mechanism underlying early-onset fetal growth restriction (eoFGR). Reduced placental function causes impaired metabolic and gaseous exchange. This unfavorable placental environment is among other processes...
5.
Khong T, Gordijn S, Schoots M, Ganzevoort W, Groom K, Coat S, et al.
Placenta . 2023 Apr; 136:26-28. PMID: 37023681
Addition of placental histopathology studies to obstetric trials is likely to be cost-effective and may reveal structural changes suggestive of functional dysfunction to explain the success or failure of a...
6.
Schoots M, Bezemer R, Dijkstra T, Timmer B, Scherjon S, Erwich J, et al.
Placenta . 2022 Oct; 129:104-110. PMID: 36283342
Introduction: Placental pathology and pregnancy complications are associated with unfavorable regulation of the maternal immune system. Although much research has been performed towards the role of immune cells like macrophages...
7.
Arjaans S, Fries M, Schoots M, Schilte C, Roofthooft M, Vrijlandt E, et al.
J Pediatr . 2022 Aug; 251:74-81.e3. PMID: 35934129
Objective: To characterize different phenotypes of early pulmonary hypertension (PH) in preterm infants and their respective associations with bronchopulmonary dysplasia (BPD) and survival. Study Design: A prospective cohort study in...
8.
Fliss M, van den Berg C, Kuijper E, Notermans D, Hendrickx A, Schoots M, et al.
Eur J Clin Microbiol Infect Dis . 2022 Jul; 41(8):1133-1138. PMID: 35790590
Infections with hypervirulent Klebsiella pneumoniae (hvKp) commonly presents with primary liver infection, bacteremia, and metastatic abscesses. Here, we present 2 cases of severe community-acquired pulmonary infections by hvKp in patients...
9.
Heimovaara J, Blommaert J, Free J, Bolt R, Gort E, Depuydt T, et al.
Clin Transl Radiat Oncol . 2022 May; 35:33-36. PMID: 35601798
Background And Purpose: Radiotherapy during pregnancy is rarely administered due to lack of data and practical challenges. This is the first detailed report of proton therapy as cancer treatment for...
10.
Smit M, Martini T, Armandari I, Bockaj I, Zomerman W, de Camargo Magalhaes E, et al.
J Cell Sci . 2022 May; 135(11). PMID: 35535520
Sonic hedgehog (SHH) medulloblastoma originates from the cerebellar granule neuron progenitor (CGNP) lineage, which depends on Hedgehog signaling for its perinatal expansion. Whereas SHH tumors exhibit overall deregulation of this...