Mirte Scheper
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Explore the profile of Mirte Scheper including associated specialties, affiliations and a list of published articles.
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10
Citations
25
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Recent Articles
1.
Specchio N, Di Micco V, Aronica E, Auvin S, Balestrini S, Brunklaus A, et al.
Epilepsia
. 2025 Feb;
PMID: 39985505
Epilepsy and autism often co-occur in genetic developmental and epileptic encephalopathies (DEEs), but their underlying neurobiological processes remain poorly understood, complicating treatment. Advances in molecular genetics and understanding the neurodevelopmental...
2.
van Vliet E, Scheper M, Mills J, Puhakka N, Szydlowska K, Ferracin M, et al.
Epilepsia
. 2024 Oct;
65(11):3406-3420.
PMID: 39352406
Objective: Structural epilepsies can manifest months or years after the occurrence of an initial epileptogenic insult, making them amenable for secondary prevention. However, development of preventive treatments has been challenged...
3.
Mesarosova L, Scheper M, Iyer A, Anink J, Mills J, Aronica E
Neurobiol Dis
. 2024 Jul;
199:106587.
PMID: 38950713
It has been shown that many miRNAs, including miR-193b-3p, are differentially expressed in Parkinson's disease (PD). Dysregulation of miR-193b-3p/PGC-1α axis may alter homeostasis in cells and can induce an inflammatory...
4.
Scheper M, Sorensen F, Ruffolo G, Gaeta A, Lissner L, Anink J, et al.
Acta Neuropathol
. 2024 May;
147(1):80.
PMID: 38714540
GABAergic interneurons play a critical role in maintaining neural circuit balance, excitation-inhibition regulation, and cognitive function modulation. In tuberous sclerosis complex (TSC), GABAergic neuron dysfunction contributes to disrupted network activity...
5.
Ravizza T, Scheper M, Di Sapia R, Gorter J, Aronica E, Vezzani A
Nat Rev Neurosci
. 2024 Mar;
25(5):334-350.
PMID: 38531962
Epilepsy remains a major health concern as anti-seizure medications frequently fail, and there is currently no treatment to stop or prevent epileptogenesis, the process underlying the onset and progression of...
6.
Romagnolo A, Dematteis G, Scheper M, Luinenburg M, Muhlebner A, Van Hecke W, et al.
Acta Neuropathol
. 2024 Feb;
147(1):48.
PMID: 38418708
Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder characterized by the development of benign tumors in various organs, including the brain, and is often accompanied by epilepsy, neurodevelopmental comorbidities...
7.
Luinenburg M, Scheper M, Sorensen F, Anink J, Van Hecke W, Korshunova I, et al.
Front Cell Neurosci
. 2023 Dec;
17:1284394.
PMID: 38089143
Introduction: Constitutive activation of the mTOR pathway, as observed in Tuberous Sclerosis Complex (TSC), leads to glial dysfunction and subsequent epileptogenesis. Although astrocytes are considered important mediators for synaptic clearance...
8.
Curatolo P, Scheper M, Emberti Gialloreti L, Specchio N, Aronica E
World J Pediatr
. 2023 Oct;
20(1):40-53.
PMID: 37878130
Background: Tuberous sclerosis complex (TSC) is a genetic disorder caused by inactivating mutations in the TSC1 and TSC2 genes, causing overactivation of the mechanistic (previously referred to as mammalian) target...
9.
Khan G, Veltkamp F, Scheper M, Hoebe R, Claessen N, Butter L, et al.
Eur J Immunol
. 2023 Aug;
53(11):e2350562.
PMID: 37597325
Levamisole (LMS) is a small molecule used in the treatment of idiopathic nephrotic syndrome (INS). The pathogenesis of INS remains unknown, but evidence points toward an immunological basis of the...
10.
Scheper M, Iyer A, Anink J, Mesarosova L, Mills J, Aronica E
Neuropathol Appl Neurobiol
. 2022 Nov;
49(1):e12864.
PMID: 36352829
Aims: Parkinson's disease (PD) is a progressive and age-dependent neurodegenerative disease characterised clinically by a variety of motor symptoms and cognitive impairment. PD was initially considered to be a grey...