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Miriam Melis

Explore the profile of Miriam Melis including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 2504
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Recent Articles
1.
Lujan M, Young-Morrison R, Aroni S, Katona I, Melis M, Cheer J
Sci Adv . 2024 Nov; 10(45):eadq5652. PMID: 39514650
The increasing prevalence of cannabis use during pregnancy has raised medical concerns, primarily related to Δ9-tetrahydrocannabinol (THC), which readily crosses the placenta and affects fetal brain development. Previous research has...
2.
Murru E, Carta G, Manca C, Verce M, Everard A, Serra V, et al.
Heliyon . 2024 Aug; 10(15):e35637. PMID: 39170117
Objective: Recent studies have demonstrated that prenatal exposure to the psychoactive ingredient of cannabis that is tetrahydrocannabinol (THC) disrupts fatty acid (FA) signaling pathways in the developing brain, potentially linking...
3.
Scheggi S, Concas L, Corsi S, Carta M, Melis M, Frau R
Neurosci Biobehav Rev . 2024 Aug; 164:105842. PMID: 39103066
Imbalances in dopamine activity significantly contribute to the pathophysiology of several neuropsychiatric disorders, including addiction, ADHD, schizophrenia, impulse control disorders, and Parkinson's Disease. Neuro(active)steroids, comprising endogenous steroids that finely modulate...
4.
Barti B, Dudok B, Kenesei K, Zoldi M, Miczan V, Balla G, et al.
Sci Adv . 2024 May; 10(22):eado0077. PMID: 38809980
While our understanding of the nanoscale architecture of anterograde synaptic transmission is rapidly expanding, the qualitative and quantitative molecular principles underlying distinct mechanisms of retrograde synaptic communication remain elusive. We...
5.
Lujan M, Young-Morrison R, Aroni S, Katona I, Melis M, Cheer J
bioRxiv . 2024 May; PMID: 38766015
The increasing prevalence of cannabis use during pregnancy has raised significant medical concerns, primarily related to the presence of Δ9-tetrahydrocannabinol (THC), which readily crosses the placenta and impacts fetal brain...
6.
Serra V, Aroni S, Bortolato M, Frau R, Melis M
Neuropharmacology . 2023 Apr; 233:109548. PMID: 37080337
Vulnerability to cocaine use disorder depends upon a combination of genetic and environmental risk factors. While early life adversity is a critical environmental vulnerability factor for drug misuse, allelic variants...
7.
Frau R, Melis M
J Neuroendocrinol . 2023 Feb; 35(2):e13240. PMID: 36810840
Sociocultural attitudes towards cannabis legalization contribute to the common misconception that it is a relatively safe drug and its use during pregnancy poses no risk to the fetus. However, longitudinal...
8.
Santoni M, Sagheddu C, Serra V, Mostallino R, Castelli M, Pisano F, et al.
Brain Behav Immun . 2023 Feb; 109:271-284. PMID: 36746342
Prenatal infections can increase the risk of developing psychiatric disorders such as schizophrenia in the offspring, especially when combined with other postnatal insults. Here, we tested, in a rat model...
9.
Testai F, Gorelick P, Aparicio H, Filbey F, Gonzalez R, Gottesman R, et al.
Stroke . 2022 Feb; 53(4):e176-e187. PMID: 35142225
Marijuana is perceived as a harmless drug, and its recreational use has gained popularity among young individuals. The concentration of active ingredients in recreational formulations has gradually increased over time,...
10.
Busquets-Garcia A, Melis M, Bellocchio L, Marsicano G
Eur J Neurosci . 2022 Feb; 55(4):903-908. PMID: 35118747
The endocannabinoid system is widely expressed both in the brain and in the periphery. This system regulates a plethora of physiological functions and is composed of cannabinoid receptors, their endogenous...