Miriam Kunkel
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Explore the profile of Miriam Kunkel including associated specialties, affiliations and a list of published articles.
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9
Citations
134
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Recent Articles
1.
Winer A, Denlinger C, Vijayvergia N, Cohen S, Astaturov I, Dotan E, et al.
Clin Colorectal Cancer
. 2020 Sep;
20(1):e43-e52.
PMID: 32972830
Background: Quinacrine plus a fluoropyrimidine has in vivo efficacy against metastatic colorectal cancer (mCRC). This phase 1b trial evaluated the combination of quinacrine plus capecitabine in patients with treatment-refractory mCRC....
2.
Kaifi J, Kunkel M, Das A, Harouaka R, Dicker D, Li G, et al.
Cancer Biol Ther
. 2015 Mar;
16(5):699-708.
PMID: 25807199
Background: Colorectal cancer (CRC) metastasectomy improves survival, however most patient develop recurrences. Circulating tumor cells (CTCs) are an independent prognostic marker in stage IV CRC. We hypothesized that CTCs can...
3.
Das A, Kunkel M, Joudeh J, Dicker D, Scicchitano A, Allen J, et al.
Cancer Biol Ther
. 2015 Mar;
16(5):709-13.
PMID: 25806877
Background: The Veridex CellSearch is an FDA-approved technology for enumerating circulating tumor cells in blood samples of metastatic colorectal cancer mCRC) patients and has prognostic value. It is important to...
4.
Kaifi J, Kunkel M, Dicker D, Joude J, Allen J, Das A, et al.
Cancer Biol Ther
. 2015 Mar;
16(5):690-8.
PMID: 25785486
Background: Metastatic spread is the most common cause of cancer-related death in colorectal cancer (CRC) patients, with the liver being the mostly affected organ. Circulating tumor cells (CTCs) are a...
5.
Allen J, Saroya B, Kunkel M, Dicker D, Das A, Peters K, et al.
Oncotarget
. 2013 Dec;
5(7):1753-60.
PMID: 24334302
Enumeration of circulating tumor cells (CTCs) by the CellSearch system provides prognostic information in metastatic colorectal cancer, regardless of metastatic site. We found that CTCs generally represent <1% of observed...
6.
Kaifi J, Kunkel M, Zhu J, Dicker D, Gusani N, Yang Z, et al.
Cancer Biol Ther
. 2013 Oct;
14(12):1174-81.
PMID: 24153154
Background: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States when combining both genders. Circulating tumor cells (CTCs) are a prognostic marker for stage...
7.
Predicting therapy response in live tumor cells isolated with the flexible micro spring array device
Gallant J, Matthew E, Cheng H, Harouaka R, Lamparella N, Kunkel M, et al.
Cell Cycle
. 2013 Jun;
12(13):2132-43.
PMID: 23759587
Cells disseminated from primary epithelial tumors into peripheral blood, called circulating tumor cells (CTCs), can be monitored to assess metastases and to provide a surrogate marker of treatment response. Here,...
8.
Zander H, Rawnaq T, von Wedemeyer M, Tachezy M, Kunkel M, Wolters G, et al.
BMC Cancer
. 2011 May;
11:189:1-7.
PMID: 21600041
Background: L1 cell adhesion molecule (CD171) is expressed in many malignant tumors and its expression correlates with unfavourable outcome. It thus represents a target for tumor diagnosis and therapy. An...
9.
Rawnaq T, Kunkel M, Bachmann K, Simon R, Zander H, Brandl S, et al.
Ann Surg Oncol
. 2010 Jul;
18(2):559-65.
PMID: 20589434
Background: A previous study identified midkine (MK) expression in primary gastrointestinal stromal tumor (GIST) as a prognostic marker. The aim of the current study was to compare serum midkine (S-MK)...