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Ming Keat Sng

Explore the profile of Ming Keat Sng including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 439
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Recent Articles
1.
Tan M, Sng M, Cheng H, Low Z, Leong B, Chua D, et al.
Cell Death Differ . 2020 Apr; 27(9):2668-2680. PMID: 32313198
The incidence of nonmelanoma skin cancer (NMSC) has been increasing worldwide. Most studies have highlighted the importance of cancer-associated fibroblasts (CAFs) in NMSC progression. However much less is known about...
2.
Chen J, Zhuang Y, Sng M, Tan N, Wahli W
Int J Mol Sci . 2019 Oct; 20(20). PMID: 31618976
Non-alcoholic fatty liver disease (NAFLD) can progress from steatosis to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation, possibly leading to cirrhosis and hepatocellular carcinoma (HCC). Mice with impaired macrophage activation,...
3.
Sng M, Chan J, Teo Z, Phua T, Tan E, Wee J, et al.
Cell Discov . 2018 Apr; 4:15. PMID: 29619245
Connective tissue diseases of the skin are characterized by excessive collagen deposition in the skin and internal organs. Fibroblasts play a pivotal role in the clinical presentation of these conditions....
4.
Tan E, Sng M, How I, Chan J, Chen J, Tan C, et al.
Oncogene . 2018 Jan; 37(15):2067-2078. PMID: 29367760
Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in...
5.
Kalailingam P, Tan H, Jain N, Sng M, Chan J, Tan N, et al.
Sci Rep . 2017 Aug; 7(1):7311. PMID: 28779153
Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously and regulates actin cytoskeleton remodeling. In order to characterize the role of N-WASP in epidermal homeostasis and cutaneous biology, we generated conditional...
6.
Teo Z, Chan J, Chong H, Sng M, Choo C, Phua G, et al.
Sci Rep . 2017 Jul; 7(1):6303. PMID: 28740178
In adult skin wounds, collagen expression rapidly re-establishes the skin barrier, although the resultant scar is aesthetically and functionally inferior to unwounded tissue. Although TGFβ signaling and fibroblasts are known...
7.
Phua T, Sng M, Tan E, Chee D, Li Y, Wee J, et al.
Sci Rep . 2017 Mar; 7:44351. PMID: 28287161
Many gastrointestinal diseases exhibit a protracted and aggravated inflammatory response that can lead to hypercytokinaemia, culminating in extensive tissue damage. Recently, angiopoietin-like 4 (ANGPTL4) has been implicated in many inflammation-associated...
8.
Chan J, Tan M, Sng M, Teo Z, Phua T, Choo C, et al.
Cell Death Dis . 2017 Jan; 8(1):e2562. PMID: 28102840
Histological inspection of visually normal tissue adjacent to neoplastic lesions often reveals multiple foci of cellular abnormalities. This suggests the presence of a regional carcinogenic signal that spreads oncogenic transformation...
9.
Jain N, Kalailingam P, Tan K, Tan H, Sng M, Chan J, et al.
Sci Rep . 2016 Dec; 6:38109. PMID: 27909303
Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously, regulates actin polymerization and is essential during mouse development. We have previously shown that N-WASP is critical for cell-ECM adhesion in fibroblasts....
10.
Tan N, Vazquez-Carrera M, Montagner A, Sng M, Guillou H, Wahli W
Prog Lipid Res . 2016 Sep; 64:98-122. PMID: 27665713
No abstract available.