Ming-Wei Wang
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Explore the profile of Ming-Wei Wang including associated specialties, affiliations and a list of published articles.
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337
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4777
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Recent Articles
1.
Yang W, Liu Q, Li Y, Li G, Lin S, Li J, et al.
Acta Pharmacol Sin
. 2025 Mar;
PMID: 40069490
Current treatments of inflammatory bowel disease (IBD) largely depend on anti-inflammatory and immunosuppressive strategies with unacceptable efficacy and adverse events. Resolution or repair agents to treat IBD are not available...
2.
Zhou Q, Zhang Z, Gao L, Li G, Zhang Y, Yang W, et al.
J Chem Theory Comput
. 2025 Mar;
PMID: 40029701
Aptamers, functional nucleic acids recognized for their high target-binding affinity and specificity, have been extensively employed in biosensors, diagnostics, and therapeutics. Conventional screening methods apply evolutionary pressure to optimize affinity,...
3.
Peng Q, Huang W, Zhang X, Pang X, Liu Y, Ruan W, et al.
ACS Omega
. 2025 Feb;
10(6):6201-6209.
PMID: 39989804
Two new tetraene lactone derivatives ( and ), two new α-pyrone derivatives ( and ), three compounds reported as natural products for the first time [an α-pyrone derivative (), an...
4.
Metoikidou C, Karnaukhov V, Boeckx B, Timperi E, Bonte P, Wang L, et al.
Cell Rep Med
. 2025 Feb;
:101973.
PMID: 39983715
Chemotherapy combined with immune checkpoint blockade has shown clinical activity in breast cancer. Response, however, occurs in only a low proportion of patients. How the immune landscape of the tumor...
5.
Yang Z, Zhou S, Zhang Q, Song Z, Liu W, Sun Y, et al.
Cell Res
. 2025 Feb;
PMID: 39966628
Equilibrioception (sensing of balance) is essential for mammals to perceive and navigate the three-dimensional world. A rapid mechanoelectrical transduction (MET) response in vestibular hair cells is crucial for detecting position...
6.
Han W, Zhou Q, Wang M
Expert Opin Drug Discov
. 2025 Feb;
:1-10.
PMID: 39953852
Introduction: China's pharmaceutical industry, which is historically centered around generic medicines, has largely transformed from imitation to innovation over the past three decades. Despite unprecedented progress, critical challenges remain such...
7.
Yang Z, Ping Y, Wang M, Zhang C, Zhou S, Xi Y, et al.
Cell
. 2025 Jan;
PMID: 39884271
Androgens, such as 5α-dihydrotestosterone (5α-DHT), regulate numerous functions by binding to nuclear androgen receptors (ARs) and potential unknown membrane receptors. Here, we report that the androgen 5α-DHT activates membrane receptor...
8.
Chou C, Lee W, Hung K, Tsai Y, Wang M, Kawczynski A, et al.
Ultrasound Med Biol
. 2025 Jan;
51(4):715-721.
PMID: 39863448
Objective: This study aimed to validate the ultrasound speckle tracking (UST) algorithm, determine the optimal probe location by comparing normalized cross-correlation (NCC) values of muscle displacement at two locations (proximal...
9.
Fan S, Li J, Zhuang J, Zhou Q, Mai Y, Lin B, et al.
J Am Chem Soc
. 2024 Dec;
147(6):4821-4832.
PMID: 39688263
Many peptide hormones adopt long α-helical structures upon interacting with their cognate receptors but often exhibit flexible conformations when unbound. Strategies that can stabilize long α-helices without disrupting their binding...
10.
Xi X, Wang Y, An G, Feng S, Zhu Q, Wu Z, et al.
Acta Pharm Sin B
. 2024 Dec;
14(11):4806-4818.
PMID: 39664437
TROP-2, a tumor-associated antigen, has been implicated in the progression of various epithelial tumors. Due to its favorable expression profile, TROP-2 has emerged as a promising target for antibody-drug conjugates...